Evidence map›Paper›PMID 41727615›Full record

ArticleResearch square2026

Single-Cell Atlas of Fetal Immune Development Across Lung, Spleen, and Umbilical Cord Blood in Nonhuman Primates.

Ilhem Messaoudi, Brianna Doratt, Sheridan Wagner, Katelyn Keen, Uriel Avila, Oleg Varlamov

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilhem MessaoudiUniversity of Kentucky College of Medicine.ORCID 0000-0003-3203-2405
Brianna DorattUniversity of Kentucky.
Sheridan WagnerUniversity of Kentucky College of Medicine.
Katelyn KeenUniversity of Kentucky College of Medicine.
Uriel AvilaOregon National Primate Research Center.
Oleg VarlamovOregon Health & Science University.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Maternal obesity and neonatal innate immunityR01AI142841 · NIAID · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM, VARLAMOV, OLEG · 2018 to 2024
$2.7M
NIAID NIH HHS R01 AI142841NIH HHS P51 OD011092
6 · The paper itself

Abstract

The fetal immune system develops within a tightly regulated environment that balances immune tolerance with readiness for postnatal antigen exposure. However, limited access to fetal tissues has constrained our understanding of immune ontogeny across distinct anatomical compartments. Here, we present a high-resolution, multi-tissue single-cell transcriptional atlas of the late-gestation (GD130-135) rhesus macaque (

Identifiers

PMID41727615
PMCPMC12919194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.