Trial reportFrontiers in surgery2026
Evaluating the impact of a modified multi-modal prehabilitation program on perioperative outcomes in Chinese patients undergoing colorectal cancer surgery.
Trial report in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aims to evaluate the feasibility and effectiveness of a modified multi-modal prehabilitation program for Chinese patients with colorectal cancer during their preoperative hospital stay. The impact on perioperative physiological function, postoperative recovery, and overall outcomes was assessed. Design: A prospective, randomized controlled trial. Methods: A prospective, randomized controlled trial was conducted with 200 patients (100 experimental, 100 control) at a tertiary hospital in Shanghai. The experimental group received a modified multi-modal prehabilitation program, including inspiratory muscle training, aerobic exercise, nutritional supplementation, and psychological support, while the control group received standard perioperative care. Primary outcomes were assessed using the 6-Minute Walk Test (6MWT) on the day before surgery and 30 days postoperatively. Secondary outcomes included postoperative hospital stay duration, time to first flatus, ambulation, oral intake, and incidence of postoperative complications. Results: The experimental group showed significantly greater improvements in 6MWT performance compared to the control group both before surgery (400.40 m vs. 383.25 m, Clinical Trial Registration: https://www.chictr.org.cn/, Identifier ChiCTR2200055764.
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