Evidence mapPaperPMID 41727960Full record

ArticleJournal of translational internal medicine2026

Migrasome as a novel organelle: Biogenesis, physiological functions, and therapeutic potential.

Rumeng Tang, Ling Zhou, Jiaran Lin, Xiangyuan Zhang, Pengfei Xie, Lili Zhang, Linhua Zhao, Xiaolin Tong

Abstract read
In one paragraph

Article in Journal of translational internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rumeng TangInstitute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Ling ZhouClinical Medical School, Chengdu University of Chinese Medicine, Chengdu, Sichuan Province, China.
Jiaran LinInstitute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiangyuan ZhangGraduate College, Beijing University of Chinese Medicine, Beijing, China.
Pengfei XieGraduate College, Beijing University of Chinese Medicine, Beijing, China.
Lili ZhangInstitute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0001-7447-0556
Linhua ZhaoInstitute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-0362-7365
Xiaolin TongInstitute of Metabolic Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migrasomes are a recently identified type of membranous organelle formed during cell migration. They are produced by migratory cells and widely distributed across various cells and tissues. Migrasomes contain abundant signaling and bioactive molecules, playing crucial roles in embryonic development, angiogenesis, material transport, mitochondrial quality control, and coagulation, as well as participating significantly in numerous pathological processes. This paper provides a detailed overview of the latest advancements in migrasome biology research, including migrasome biogenesis, physiological functions, isolation, and identification, and their roles in the onset, progression, diagnosis, and treatment of clinical diseases. In addition, we propose novel hypotheses and outline future research directions addressing current challenges and potential clinical applications of migrasomes, which may inform their utilization in future clinical diagnostics and therapeutics.

Indexed as

biogenesismigrasomeorganellesphysiological functionstherapeutic potential

Identifiers

PMID41727960
PMCPMC12916279

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.