Evidence map›Paper›PMID 41728249›Full record

ArticleACG case reports journal2026

Aggressive Right-Sided Colon Cancer in a Young Adult: Triple-Whammy Mutations (POLE, KRAS, BRCA1/2) Highlight Emerging Genetic Associations.

Ravi Patel, Ganesh Kumar, Yash Shah, Dushyant Singh Dahiya, Sumant Inamdar

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ravi PatelDepartment of Internal Medicine, Trinity Health Oakland/Wayne State University, Pontiac, MI.ORCID https://orcid.org/0009-0003-5279-1027
Ganesh KumarDepartment of Medicine, Chandka Medical College, Larkana, Pakistan.
Yash ShahDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR.
Dushyant Singh DahiyaDivision of Gastroenterology, Hepatology and Motility, The University of Kansas School of Medicine, Kansas City, KS.
Sumant InamdarDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRCA mutations are well established in breast and ovarian cancers and increasingly recognized in colorectal cancer (CRC), particularly

Indexed as

BRCA1 mutationBRCA 2 mutationcolorectal cancerearly-onset CRChigh tumor mutational burdenimmune checkpoint inhibitorKRAS mutationmicrosatellite stablenext-generation sequencingPARP inhibitorPOLE mutationright-sided colon adenocarcinoma

Identifiers

PMID41728249
PMCPMC12922904

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.