Evidence mapPaperPMID 41728263Full record

ArticleBrain communications2026

Comprehensive evaluation of EEG spatial sampling, head modelling and parcellation effects on network alterations in idiopathic generalized epilepsy.

Christina Stier, Markus Loose, Carmen Loew, Marysol Segovia-Oropeza, Sangyeob Baek, Holger Lerche, Niels K N Focke

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In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christina StierClinic of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID https://orcid.org/0000-0001-5707-4885
Markus LooseClinic of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.
Carmen LoewClinic of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.
Marysol Segovia-OropezaClinic of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.
Sangyeob BaekMEG-Center, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Holger LercheDepartment of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.ORCID https://orcid.org/0000-0002-1783-8710
Niels K N FockeClinic of Neurology, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID https://orcid.org/0000-0001-5486-6289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic generalized epilepsy is characterized by marked brain network alterations as assessed using electrophysiology. Logistical challenges and the need for a volumetric MRI often hinder the clinical application of high-density EEG or magnetoencephalography. This study investigates the influence of EEG channel density and the head model on brain metrics derived from 256-channel EEG and 19-channel routine EEG in two samples balanced for age and sex. First, we evaluated resting-state data from 35 individuals with idiopathic generalized epilepsy and 54 healthy controls collected using the 256-channel setup. Data were analysed at full density and then iteratively downsampled to lower densities. Source reconstruction was performed either using individual MRI data or a standard brain template and dynamic imaging of coherent sources. We assessed EEG power and connectivity (imaginary part of coherency) group differences at all channel compositions, head model types and parcellations (cortical vertices, anatomical and network parcellations). Second, a routine sample recorded with 19 channels was analysed to validate findings in a real epilepsy monitoring scenario (71 patients, 43 controls). We found that lower-density arrays reliably identified global group differences for both power and connectivity and in frequency bands for which the strongest effects were observed. The spatial similarity of the results for the 256 channels set and those with fewer channels were good to moderate for power (

Indexed as

connectivityhigh-densitylow-densitypowerresting-state

Identifiers

PMID41728263
PMCPMC12917543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.