Evidence map›Paper›PMID 41728842›Full record

ArticleHistology and histopathology2026

Nicotinamide adenine dinucleotide phosphate hydrogen oxidase 2 exacerbates abdominal aortic aneurysm formation by inducing oxidative stress through autophagy inhibition.

Xiaoliang Yin, Dehai Lang, Songjie Hu

Abstract read
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In one paragraph

Article in Histology and histopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoliang YinDepartment of Vascular Surgery, Ningbo No. 2 Hospital, Wenzhou Medical University, Ningbo, China.
Dehai LangDepartment of Vascular Surgery, Ningbo No. 2 Hospital, Wenzhou Medical University, Ningbo, China.
Songjie HuDepartment of Vascular Surgery, Ningbo No. 2 Hospital, Wenzhou Medical University, Ningbo, China. songjie606@yeah.net.

Funding

Clinical Key Speciality Construction Project of Zhejiang Province, China 2026004Medical Scientific Research Foundation of Zhejiang Province 2024KY1549Medical Scientific Research Foundation of Zhejiang Province 2024KY1558Medical Scientific Research Foundation of Zhejiang Province 2024KY1559Medical Scientific Research Foundation of Zhejiang Province, China 2024KY1549Medical Scientific Research Foundation of Zhejiang Province, China 2024KY1558Medical Scientific Research Foundation of Zhejiang Province, China 2024KY1559NINGBO Leading Medical and Health Discipline 2026-A25
6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) has high mortality and enhanced oxidative stress; autophagy inhibition accelerates its formation. Nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidase 2 (NOX2) is responsible for generating reactive oxygen species (ROS). The aim is to clarify the mechanism of NOX2-mediated autophagy in AAA. Subcutaneous angiotensin II (AngII) infusion in ApoE

Indexed as

Aortic Aneurysm, AbdominalAutophagyNADPH Oxidase 2Oxidative StressAngiotensin IIAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleReactive Oxygen SpeciesAngiotensin IICybb protein, mouseNADPH Oxidase 2Reactive Oxygen Species

Identifiers

PMID41728842

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.