Evidence map›Paper›PMID 41728893›Full record

Observational studyESC heart failure2026

Diabetes increases the risk of heart failure in myocarditis: a propensity-matched nationwide database analysis.

Rayane El-Khoury, Shadi Mahmoud, Soha Dargham, Ziyad Mahfoud, Amin Jayyousi, Jassim Al Suwaidi, Charbel Abi Khalil

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in ESC heart failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rayane El-KhouryDepartment of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.
Shadi MahmoudDepartment of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.
Soha DarghamDepartment of Medical Education, Weill Cornell Medicine-Qatar, Doha, Qatar.
Ziyad MahfoudBiostatistics Core, Weill Cornell Medicine-Qatar, Doha, Qatar.
Amin JayyousiDepartment of Endocrinology, Hamad Medical Corporation, Doha, Qatar.
Jassim Al SuwaidiHeart Hospital, Hamad Medical Corporation, Doha 3050, Qatar.
Charbel Abi KhalilDepartment of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar.ORCID 0000-0002-1428-6324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe impact of diabetes on non-atherosclerotic cardiac disease has not been studied extensively. We aimed to assess the in-hospital and long-term effects of diabetes in patients hospitalized for myocarditis.

methodsThe Nationwide Readmissions Database (2016-2020) was used to identify adults hospitalized with a primary diagnosis of myocarditis. Patients were stratified by the presence of diabetes, and those discharged alive were followed for a calendar year. The primary outcome was in-hospital mortality. Secondary outcomes included in-hospital ventricular fibrillation, ventricular tachycardia, acute renal failure, cardiogenic shock, heart failure, and one-year all-cause readmission, readmission for heart failure, and mortality. Multivariable logistic and Cox regression models were applied, and propensity score matching was performed as a sensitivity analysis.

resultsAmong 8826 adults with myocarditis, 951 (11%) had diabetes. Compared with patients without diabetes, those with diabetes were older, had a higher prevalence of comorbidities, and showed an increased adjusted risk of in-hospital acute renal failure [aOR = 1.74 (95% CI: 1.42-2.12)], heart failure [aOR = 1.62 (95% CI: 1.37-1.91)], cardiogenic shock [aOR = 1.36 (95% CI: 1.04-1.78)], but not of mortality, ventricular fibrillation, and ventricular tachycardia. In one year, diabetes was not associated with higher adjusted risks of all-cause readmission or mortality [aHR = 0.81 (95% CI: 0.41-1.60) and aHR = 0.81 (95% CI: 0.68-0.97), respectively]. However, it was associated with a higher risk of readmission for heart failure [aHR = 1.16 (95% CI: 1.02-1.31)]. These associations remained consistent in propensity score-matched analyses.

conclusionDiabetes independently increases the risk of in-hospital and one-year heart failure in patients with myocarditis.

Indexed as

Diabetes MellitusHeart FailureMyocarditisPropensity ScoreAdultDatabases, FactualFemaleHospital MortalityHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateCardiologyCardiovascular diseaseDiabetesMyocarditisNational readmission database

Identifiers

PMID41728893
PMCPMC13244792

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.