Evidence map›Paper›PMID 41729299›Full record

SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Early versus delayed fixation of maxillofacial fractures in polytrauma: a systematic review.

Jane Chen, Karen Vuong, Zsolt J Balogh

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jane ChenDepartment of Oral Maxillofacial Surgery, Monash Health, Melbourne, VIC, Australia.
Karen VuongDepartment of Plastic and Reconstructive Surgery, Western Health, Melbourne, VIC, Australia.
Zsolt J BaloghDepartment of Traumatology, John Hunter Hospital, Newcastle, NSW, Australia. zsolt.balogh@health.nsw.gov.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaxillofacial fractures are common in polytrauma, and these patients often require intensive care unit (ICU) admission until delayed definitive surgical management. This review aims to evaluate the scientific evidence on timing of definitive internal fracture fixation of maxillofacial fractures in polytrauma. We hypothesise that delayed definitive surgery is associated with better outcomes.

methodsThis systematic review was conducted in accordance with the PRISMA protocol. MEDLINE, EMBASE, Scopus, CINAHL and PubMed were searched from inception to July 2025 for articles in English reporting timing of facial fracture fixation in polytrauma cohorts. Two reviewers independently screened studies and extracted data on patient characteristics, injury severity, fixation timing, and patient outcomes. Risk of bias was assessed using the Newcastle-Ottawa Scale.

results359 studies were initially identified. After applying inclusion and exclusion criteria, three retrospective studies (total 365 patients) were included. Timing definitions of fixation varied, with early fixation intervals ranging from ≤ 24 h to ≤ 72 h. Surgical-site infection rates ranged from 0 to 12.7% (early) and 4.8–14.4% (delayed). No significant differences emerged in anatomical reduction, reoperation rates, or complications between groups. Hospital and ICU length of stay, ventilator days and mortality rates were comparable. Studies were heterogeneous and subject to high risk of bias.

conclusionsThe available low-quality evidence does not support a clear advantage of the current practice of delayed fixation of facial fractures in polytrauma patients. Quality prospective studies with predefined inclusion criteria, clear consensus about the cut-off for early timing of surgery and standardised outcome measures are required.

Indexed as

Fracture Fixation, InternalMaxillofacial InjuriesMultiple TraumaSkull FracturesTime-to-TreatmentHumansLength of StayTime FactorsTreatment DelayMaxillo-facial traumaMultiple injuriesPolytraumaTrauma centreTrauma surgeryTrauma system

Identifiers

PMID41729299
PMCPMC12929254

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.