Evidence map›Paper›PMID 41729356›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Impact of underlying kidney disease on the outcomes of cardiac implantable electronic devices in patients with heart failure.

Amith Seri, Abdul Rasheed Bahar, Soumya Kambalapalli, George G Kidess, Mohamad Hasan Jawadi, Yasemin Bahar, Alaa Diab, M Chadi Alraies

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Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Amith SeriDepartment of Hospital Medicine, Princeton Community Hospital/West Virginia University, Princeton, WV, USA.
Abdul Rasheed BaharDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, MI, USA.
Soumya KambalapalliDepartment of Cardiology/Advanced Cardiac Imaging, UCLA-Harbor/The Lundquist Institute, Torrance, CA, USA.
George G KidessWayne State University School of Medicine, Detroit, MI, USA.
Mohamad Hasan JawadiDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, MI, USA.
Yasemin BaharWayne State University, Detroit, MI, USA.
Alaa DiabDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, MI, USA.
M Chadi AlraiesCardiovascular Institute, Detroit Medical Center, DMC Heart Hospital, Detroit, MI, USA. alraies@hotmail.com.ORCID http://orcid.org/0000-0002-7874-4566

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure (HF) and kidney disease commonly coexist and are associated with high mortality, as kidney disease is known to increase the risk of arrhythmias and sudden cardiac death in HF patients. The use of cardiac implantable electronic devices (CIEDs) has proven to be an effective therapy for HF patients. However, the literature on the outcomes of these devices in HF patients with underlying kidney disease is limited, given their exclusion from major trials.

methodsUtilizing the National Inpatient Sample (NIS) database, hospitalizations with a discharge diagnosis of HF and CIEDs were identified from 2016 to 2021 and stratified into groups of no kidney disease, chronic kidney disease (CKD), and end-stage renal disease (ESRD). Baseline characteristics were compared, and adjusted outcomes were obtained.

resultsA total of 24,250 HF patients with CIED were identified and divided into HF group with no kidney disease (n = 14,485), HF-CKD (n = 8990) (37%), and HF-ESRD (n = 775). Compared to patients with HF with no kidney disease, those with CKD and ESRD showed higher odds of in-hospital mortality and cardiogenic shock. Patients with HF and ESRD had higher odds of sudden cardiac arrest and mechanical circulatory support utilization compared to those with no kidney disease.

conclusionUnderlying kidney disease is associated with increased mortality and complications in HF patients having CIED implantations. Further prospective studies and trials are needed to help identify the appropriate use of CIED in HF patients with kidney disease.

Indexed as

Defibrillators, ImplantableHeart FailureKidney Failure, ChronicPacemaker, ArtificialRenal Insufficiency, ChronicAgedDeath, Sudden, CardiacFemaleHospital MortalityHumansMaleMiddle AgedTreatment OutcomeUnited StatesCardiac implantable electronic devicesHeart failureKidney disease

Identifiers

PMID41729356

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.