ReviewJournal of Korean Neurosurgical Society2026
The Role of Gut Microbiota-Derived Extracellular Vesicles in Post-Anesthesia Neuroinflammation and Cognitive Impairment.
Review in Journal of Korean Neurosurgical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroinflammation and cognitive impairment during the perioperative period significantly affect patient recovery, making them critical targets for therapeutic intervention. Recently, there has been growing interest in gut-derived exosomes (bacterial extracellular vesicles, BEVs) and their potential to modulate the central nervous system. The gut-brain axis, a vital pathway linking the gut to the central nervous system, offers a unique lens through which to explore the role of BEVs in nerve regeneration. This study investigates the biological properties and functions of BEVs during the perioperative period, focusing on their mechanisms in promoting post-anesthesia nerve recovery, including anti-inflammatory effects, neurotrophic support, and metabolic reprogramming. Additionally, the study explores potential BEV-based therapeutic approaches, current challenges in research, and future directions, aiming to provide novel insights and rationales for clinical application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.