ArticleJournal of nanobiotechnology2026
Garlic-derived exosome-like nanovesicle core-shell platform for sequential infection treatment and tissue repair.
Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Biofluid-derived exosomes as next-generation biotherapeutic platforms to combat multidrug-resistant bacterial infections.Regenerative biomaterials · 2026Review
- Plant-Derived Exosomes in Aesthetic Medicine.Biomaterials research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Infectious tissue damage evolves through a stage-dependent cascade, progressing from initial pathogen invasion and immune dysfunction to subsequent failure in tissue regeneration. While nanotechnology offers promising strategies for infection control, its inability to dynamically adapt to the changing pathological environment remains a limitation. Here, a programmable single-particle core-shell nanoplatform (Z-Lyc@ELP) was constructed by integrating hierarchical structural separation with environment-responsive mechanisms, enabling sequential intervention aligned with infection progression. The outer shell, composed of unsaturated phospholipid-doped garlic-derived exosome-like nanovesicles (GELNs), exhibits reactive oxygen species (ROS) responsiveness. At the early stage of infection, it rapidly releases polymyxin B (PMB) and immunoregulatory molecules to remodel the pathogenic microenvironment. As lesion acidification deepens, the ZIF-8 core gradually decomposes, releasing lycopene (Lyc) and Zn
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.