Evidence map›Paper›PMID 41732278›Full record

ArticleiScience2026

YBX1 promotes angiogenesis after myocardial infarction by stabilizing HIF1α mRNA via m

Fangfang Bi, Tong Yu, Hanyu Liu, Miao Cao, Yijie He, Jin Li, Haoshu Wang, Chengyu Kong, Hongwen Xiao, Hua Tian and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fangfang BiNHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, The Fourth Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China.
Tong YuShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China.
Hanyu LiuShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China.
Miao CaoDepartment of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yijie HeDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Jin LiDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Haoshu WangShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China.
Chengyu KongShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China.
Hongwen XiaoDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Hua TianDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Fu LiuDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Yun WuDepartment of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yuhong ZhouDepartment of Basic Medicine, Xiamen Medical College, Xiamen, Fujian 361023, China.
Hongli ShanShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai 201620, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is essential for myocardial repair after myocardial infarction (MI). While Y-box binding protein 1 (YBX1) is well-established in cancer biology, its role in post-MI angiogenesis remains unknown. Here, we show that YBX1 expression is increased in endothelial cells after MI, with higher levels observed in the peri-infarct region, and is also induced in hypoxic HUVECs.

Indexed as

BiochemistryCell biologyHealth sciencesMolecular mechanism of gene regulation

Identifiers

PMID41732278
PMCPMC12924730

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.