Evaluating the implementation of a deprescribing intervention in Swiss nursing homes: An observational study using qualitative and quantitative methods.

Stephanie Mena, Julie Dubois, Florent Macé, Joanna Moullin, Damien Cateau, Marie Schneider, Anne Niquille

Abstract read

In one paragraph

Article in Exploratory research in clinical and social pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Codesigned STAIR OF KNOWLEDGE intervention to prevent pressure ulcers, malnutrition, poor oral health and falls in Swedish nursing homes: an external pilot cluster randomised controlled study.BMJ open · 2026
Trial

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephanie MenaCommunity Pharmacy, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Julie DuboisInstitute Department of Epidemiology and Health Systems, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Florent MacéCommunity Pharmacy, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Joanna MoullinCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Perth, Australia.

Damien CateauCommunity Pharmacy, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Marie SchneiderSchool of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.

Anne NiquilleCommunity Pharmacy, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deprescribing, the withdrawal of inappropriate medications, is an appropriate approach to addressing polypharmacy in older adults. However, implementing deprescribing interventions in routine practice remains challenging. This study evaluated the implementation of medication reviews focused on deprescribing, called Individual Deprescribing Intervention (IDeI), in Swiss nursing homes. Using a hybrid type 2 effectiveness-implementation design, we conducted a qualitative evaluation through semi-structured interviews with nurses, physicians and pharmacists, based on the Framework for the Implementation of Pharmacy Services (FISpH). Quantitative data were collected from administrative sources. IDeI was successfully implemented in six of seven nursing homes and most healthcare professionals (HCPs) were satisfied. Fidelity was considered good, as only minor intervention adaptations were made. Five main determinants influenced implementation: interprofessional collaboration (facilitator), pharmacist access to medical records (facilitator), motivation fostered by the structured process (facilitator), resident/family resistance to deprescribing (barrier), and resident/staff turnover (barrier). Integration into routine practice was deemed feasible but sustained in only two nursing homes one year later. IDeI achieved good reach, adoption and HCP satisfaction, providing insights for sustainability. Recommendations include financial incentives, pharmacist training, audit & feedback and greater involvement of residents/families. Findings align with existing literature, emphasizing the need to reinforce interprofessional collaboration and long-term maintenance strategies.

Indexed as

DeprescribingImplementation scienceLong-term careNursing homesQualitative and quantitative methods

Identifiers

PMID41732298

DOI10.1016/j.rcsop.2026.100713

PMCPMC12924747

What Socratic holds

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.