Evidence map›Paper›PMID 41733356›Full record

ArticleInfection and immunity2026

Myeloid-derived interleukin-10 induced by thrombospondin-1 mediates host defense and regulates inflammation during acute bacterial lung infection.

Agnes Jara-Collao, Francisca Román, Gonzalo Torres-Ayala, Felipe Novoa, Cynthia Moreno-Quidecoy, Aillairlyn Jara, Pablo A González, Susan M Bueno, Alexis M Kalergis, Hernán F Peñaloza

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Agnes Jara-Collao *Millennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Francisca Román *Millennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Gonzalo Torres-AyalaMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Felipe NovoaMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Cynthia Moreno-QuidecoyMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Aillairlyn JaraMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pablo A GonzálezMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID 0000-0001-7709-6870
Susan M BuenoMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID 0000-0002-7551-8088
Alexis M KalergisMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Hernán F PeñalozaMillennium Institute on Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.ORCID 0000-0002-1593-678X

Funding

Agencia Nacional de Investigación y Desarrollo FONDECYT de Iniciación 11230573Agencia Nacional de Investigación y Desarrollo FONDECYT Regular 1231851Agencia Nacional de Investigación y Desarrollo FONDECYT Regular 1231905Agencia Nacional de Investigación y Desarrollo FONDECYT Regular 1240971Agencia Nacional de Investigación y Desarrollo Millennium Institute on Immunology and Immunotherapy, ANID - Millennium Science Initiative Program ICN2021_045 (former P09/016-F)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

InflammationInterleukin-10Pneumonia, BacterialPseudomonas InfectionsThrombospondin 1AnimalsLungMiceMice, Inbred C57BLMice, KnockoutMonocytesNeutrophilsPseudomonas aeruginosaIL10 protein, mouseInterleukin-10Thbs1 protein, mouseThrombospondin 1interleukin-10neutrophilsPseudomonas aeruginosathrombospondin-1

Identifiers

PMID41733356
PMCPMC13081729

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.