Evidence map›Paper›PMID 41733821›Full record

ReviewDiscover nano2026

Quantum dot enhanced photonic biosensors for single cell analysis from synthesis to clinical application.

Mohammad Hosseini Hooshiar, Javad Hosseini Hooshiar, Saeed Hosseini Hooshiar

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohammad Hosseini HooshiarDepartment of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Smh.hooshiar@gmail.com.
Javad Hosseini HooshiarSabzevar University of Medical Sciences, Tehran, Iran.
Saeed Hosseini HooshiarSabzevar University of Medical Sciences, Tehran, Iran. saeed_hooseiny@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quantum dot (QD)-enhanced optical biosensors are very sensitive tools for analyzing single cells. Heavy metal-free alternatives, such as indium phosphide and carbon-based QDs, address safety concerns while achieving high quantum efficiency. Photonic enhancement techniques provide 240-fold signal amplification and quality factors of up to 7000, allowing femtomolar detection limits. However, clinical translation encounters manufacturing scalability and stability problems in complex biological matrices. This review discusses synthetic techniques, surface functionalization, and clinical implementation, highlighting important challenges and potential for improving QD-based biosensors.

Indexed as

BiomarkersBiosensorsCancerDiagnosticsFluorescenceNanoparticlesQuantum dots

Identifiers

PMID41733821
PMCPMC12932788

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.