Evidence mapPaperPMID 41733834Full record

ReviewCurrent HIV/AIDS reports2026

Obesity and Weight Management in HIV: Epidemiology, Complications, and Emerging Treatments.

Luke Pryke, John R Koethe, Samuel Bailin

Abstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke PrykeDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, A-2200 MCN, 1161 21st Avenue South, Nashville, TN, 37232, USA.
John R KoetheDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, A-2200 MCN, 1161 21st Avenue South, Nashville, TN, 37232, USA.
Samuel BailinDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, A-2200 MCN, 1161 21st Avenue South, Nashville, TN, 37232, USA. Samuel.bailin@vumc.org.

Funding

Tennessee Center for AIDS Research (TN-CFAR)P30AI110527 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$1.7M
Adipose Tissue T Cell Polarization and Metabolic Health in Persons Living with HIVK23DK135414 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$185k
NIAID NIH HHS P30 AI110527NIDDK NIH HHS K23 DK135414
6 · The paper itself

Abstract

purpose of reviewPeople living with HIV (PLWH) on contemporary antiretroviral therapy experience high rates of overweight/obesity, which predisposes to cardiometabolic disease and multiple other conditions with negative health consequences in this aging population. We aim to summarize the epidemiology and pathophysiology of obesity in PLWH and review recent advances in the therapeutic management of obesity. RECENT

findingsThe prevalence of overweight/obesity in PLWH mirrors long-standing trends in the general population. Obesity and weight gain have a complex, multifactorial pathogenesis and directly mediate detrimental metabolic changes that are common in PLWH. While lifestyle changes are important, surgical weight loss and recent advances in medical therapeutics are more effective at reducing obesity and obesity-related complications. Obesity in PLWH substantially increases the risk for cardiometabolic complications and poor health outcomes. Surgical and medical weight loss interventions are effective treatments to reduce obesity and obesity-related complications, though further research in PLWH is needed to define optimal management.

Indexed as

HIV InfectionsObesityHumansPrevalenceWeight LossAntiretroviral therapyGlucagon-like peptide-1 receptor agonistHIVObesityWeight gainWeight management

Identifiers

PMID41733834
PMCPMC12932276

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.