Evidence map›Paper›PMID 41734147›Full record

ReviewPLOS global public health2026

Advancing global health access through market shaping: Cases and learnings.

Claire M Wagner, Amy Lin, Sabin Nsanzimana, Janet K Ginnard, Jayasree K Iyer, Mary-Ann Etiebet, David Ripin, Sandeep Juneja, Dominic Hein, Gian Gandhi and 1 more

Abstract readReview
In one paragraph

Review in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claire M WagnerAvenir Management Partners, Boston, Massachusetts, United States of America.ORCID https://orcid.org/0000-0002-5886-4130
Amy LinCenter for Innovation and Impact, USAID, Washington, DC, United States of America.ORCID https://orcid.org/0009-0004-8816-0777
Sabin NsanzimanaMinistry of Health, Government of Rwanda, Kigali, Rwanda.
Janet K GinnardUnitaid, Geneva, Switzerland.
Jayasree K IyerAccess to Medicine Foundation, Amsterdam, Netherlands.
Mary-Ann EtiebetVital Strategies, New York, New York, United States of America.ORCID https://orcid.org/0009-0000-3906-5168
David RipinClinton Health Access Initiative, Dorchester, Massachusetts, United States of America.
Sandeep JunejaMarket Access, TB Alliance, New York, New York, United States of America.ORCID https://orcid.org/0000-0002-3735-3120
Dominic HeinVaccine Programmes & Markets, Gavi, The Vaccine Alliance, Geneva, Switzerland.
Gian GandhiGlobal Development, Gates Foundation, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0002-9630-5866
Charles B HolmesCenter for Innovation in Global Health, Georgetown University, Washington District of Columbia, United States of America.ORCID https://orcid.org/0000-0002-7924-6761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New health products have contributed to major improvements in public health, but many clinically effective interventions still face delays in reaching low- and middle-income countries (LMICs). Market shaping approaches have emerged as a set of tools designed to address such access gaps by influencing prices, supply, and demand. Drawing on practitioner experience and illustrative cases, this paper examines how market shaping mechanisms have been used to expand access to pharmaceutical products in LMICs. We review examples including dolutegravir, rifapentine-based tuberculosis preventive therapy, pretomanid for drug-resistant tuberculosis, the RTS,S malaria vaccine, and Rwanda's hepatitis C program, alongside ecosystem-level interventions such as revolving funds and initiatives to strengthen regional manufacturing. Across these cases, we suggest generalizable lessons and describe trade-offs related to donor dependence, supplier concentration, and timing of interventions. The paper identifies priorities for empirical research to assess the performance, risks, and applicability of market shaping tools as global health needs and resource environments evolve.

Identifiers

PMID41734147
PMCPMC12931745

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.