Evidence map›Paper›PMID 41736437›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2026

Study of event-related potentials to identify differences in verbal working memory in patients with mild cognitive impairment with different Traditional Chinese Medicine syndromes.

Liu Yong, Hou Junlin, Zhao Ziwei, Yan Guoli, L I Ning, Zhao Chuan, Zhou Liyue, Zhan Xianghong

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Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Liu YongDepartment of Physiology, School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Hou JunlinDepartment of Basic Teaching for Integrated Traditional Chinese and Western Medicine, Traditional Chinese Medicine (Zhong Jing) School, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Zhao ZiweiResearch and Experimental Center, Traditional Chinese Medicine (Zhong Jing) School, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yan GuoliDepartment of Preventive Medicine, School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China.
L I NingDepartment of Basic Teaching for Integrated Traditional Chinese and Western Medicine, Traditional Chinese Medicine (Zhong Jing) School, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Zhao ChuanDepartment of Preventive Medicine, School of Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Zhou LiyueDepartment of Management Science and Engineering, College of Management, Henan university of technology, Zhengzhou 450001, China.
Zhan XianghongDepartment of Basic Teaching for Integrated Traditional Chinese and Western Medicine, Traditional Chinese Medicine (Zhong Jing) School, Henan University of Chinese Medicine, Zhengzhou 450046, China.

Funding

Effects and Mechanism of Liver's Failing to Facilitate the Coursing of Qi on Decline Process of Cognitive Function of Normal People and Patients with MCI 81873208National Natural Science Foundation of China-funded Project: Study on Mechanism of "Smoothing The Liver Therapy" on Working Memory of the Patients with Mild Cognitive Impairment Caused by Negative Emotion Regulation 81473556
6 · The paper itself

Abstract

objectiveTo examine the differences in cognitive processing between patients with mild cognitive impairment (MCI) of different Traditional Chinese Medicine (TCM) syndrome types to provide evidence supporting the TCM typing of MCI.

methodsParticipants were screened using a battery of scales for spleen and kidney deficiency (SKD) / liver

resultsThere were no statistically significant differences in the accuracy or reaction times of the behavioral data of the groups. Regarding ERP data, the SKD group had a shorter P2 latency than the LQS and NC groups, while the latter two groups did not differ statistically. The SKD group had a shorter N2 latency than the NC group, while the SKD group did not differ from the LQS group. The SKD and LQS groups had a shorter P3 latency than the NC group.

conclusionOur study offers objective evidence of the distinction between the types of TCM syndrome. Different types of TCM syndromes produce different disease mechanisms, resulting in brain damage with different presentations of cognitive impairment and cognitive processing characteristics.

Indexed as

Cognitive DysfunctionEvoked PotentialsMemory, Short-TermAgedElectroencephalographyFemaleHumansMaleMedicine, Chinese TraditionalMiddle Agedevent-related potentialmild cognitive impairmentN-back paradigmTraditional Chinese Medicine syndrome types

Identifiers

PMID41736437
PMCPMC12884489

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.