Evidence map›Paper›PMID 41736788›Full record

ArticleFrontiers in cellular and infection microbiology2026

Disruption of cellular calcium homeostasis by duck Tembusu virus facilitates viral replication via AMPK pathway activation.

Ziding Yu, Xiaoyong Chen, Wenxiao Zhuo, Zhenxing Ma, Zejun Xu, Kuanhui Liu, Julong Wang, Ting Li, Guangshuang Zhu, Benzhong Wang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ziding Yu *Wuhu Vocational Technical University, Wuhu, China.
Xiaoyong Chen *Xingzhi College, Zhejiang Normal University, Jinhua, China.
Wenxiao ZhuoWuhu Vocational Technical University, Wuhu, China.
Zhenxing MaWuhu Vocational Technical University, Wuhu, China.
Zejun XuWuhu Vocational Technical University, Wuhu, China.
Kuanhui LiuWuhu Vocational Technical University, Wuhu, China.
Julong WangWuhu Vocational Technical University, Wuhu, China.
Ting LiWuhu Vocational Technical University, Wuhu, China.
Guangshuang ZhuWuhu Vocational Technical University, Wuhu, China.
Benzhong WangWuhu Vocational Technical University, Wuhu, China.
Ran XiongWuhu Vocational Technical University, Wuhu, China.
Chao LiWuhu Vocational Technical University, Wuhu, China.
Haiyan ZhangWuhu Vocational Technical University, Wuhu, China.
Jingliang SuKey Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The flavivirus Duck Tembusu virus (DTMUV) exhibits high pathogenicity and transmissibility, posing a severe threat to the poultry industry in China and Southeast Asia. Although the molecular mechanisms of DTMUV pathogenesis remain unclear, its potential to disrupt intracellular calcium ion (Ca² Methods: Fluo-4AM staining and flow cytometry of duck embryo fibroblasts (DEFs) were used to detect cytoplasmic Ca² Results: DTMUV infection significantly increased cytoplasmic Ca² Conclusions: DTMUV disrupts host Ca²

Indexed as

AMP-Activated Protein KinasesCalciumFlavivirusFlavivirus InfectionsHomeostasisRNA ReplicationVirus ReplicationAnimalsCalcium Channel BlockersDucksEgtazic AcidFibroblastsSignal Transduction1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl esterAMP-Activated Protein KinasesCalciumCalcium Channel BlockersEgtazic AcidAMPKantiviral targetCa2+ homeostasisDTMUVVGCCsviral RNA replication

Identifiers

PMID41736788
PMCPMC12926480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.