Evidence map›Paper›PMID 41736862›Full record

ReviewiScience2026

Bisphenol A and its analogues in thyroid diseases: Evidence from dysfunction, autoimmunity, and cancer.

Xu Hao, Hongliang Cao, Boya Shi, Chenyang Bai, Xuyao Liu, Xianying Meng

Abstract readReview
In one paragraph

Review in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xu HaoThyroid Surgery Department, General Surgery Center, First Hospital of Jilin University, Changchun, China.
Hongliang CaoDepartment of Urology, The First Hospital of Jilin University, Changchun, China.
Boya ShiThyroid Surgery Department, General Surgery Center, First Hospital of Jilin University, Changchun, China.
Chenyang BaiChina-Japan Union Hospital of Jilin University, Jilin University, Changchun 130033, China.
Xuyao LiuThyroid Surgery Department, General Surgery Center, First Hospital of Jilin University, Changchun, China.
Xianying MengThyroid Surgery Department, General Surgery Center, First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) and its analogues are widely used industrial chemicals in the production of polycarbonate plastics, epoxy resins, and related polymeric materials. Their extensive production and application have led to pervasive environmental contamination, enabling human exposure via ingestion, inhalation, and dermal absorption. As endocrine disruptors, BPA and its analogues (such as bisphenol S and bisphenol F) can influence thyroid homeostasis through interference with hormone synthesis, metabolism, and receptor signaling pathways. Recent studies suggest that exposure to bisphenols may contribute to thyroid dysfunction, autoimmune thyroid disease, and possibly thyroid carcinogenesis. Although some BPA alternatives appear to exert thyroid disrupting effects comparable to BPA, limited epidemiological evidence precludes a clear assessment of their relative safety. Given the ongoing rise in global bisphenol exposure, clarifying molecular mechanisms, defining susceptible subpopulations, and improving regulatory oversight are critical steps toward reducing thyroid-related health risks.

Indexed as

EndocrinologyHealth sciencesInternal medicineMedicine

Identifiers

PMID41736862
PMCPMC12927062

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.