Evidence mapPaperPMID 41736950Full record

ReviewFrontiers in physiology2026

Enzymes that generate and regulate intracellular persulfides and polysulfides: mechanistic insights and inhibitors.

Ko Hirabayashi, Eita Sasaki, Hisashi Ohno, Orie Takayama, Sota Yamada, Kenjiro Hanaoka

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ko Hirabayashi *Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Eita Sasaki *Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Hisashi OhnoGraduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Orie TakayamaGraduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Sota YamadaGraduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Kenjiro HanaokaGraduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive sulfur species (RSS), which include various persulfides and polysulfides, are generated by multiple enzymes

Indexed as

mitochondrial respirationpersulfidepolysulfideprotein persulfidereactive sulfur speciesselective inhibitorsulfide oxidationtranssulfuration pathway

Identifiers

PMID41736950
PMCPMC12926118

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.