Evidence map›Paper›PMID 41736997›Full record

ArticleBioinformatics advances2026

Fast phenotype simulation for genotype representation graphs.

Aditya Syam, Chris Adonizio, Xinzhu Wei

Abstract read
In one paragraph

Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Aditya SyamDepartment of Computational Biology, Cornell University, Ithaca, NY 14850, United States.
Chris AdonizioDepartment of Computational Biology, Cornell University, Ithaca, NY 14850, United States.
Xinzhu WeiDepartment of Computational Biology, Cornell University, Ithaca, NY 14850, United States.ORCID https://orcid.org/0000-0001-8184-7016

Funding

Dissecting the genetics and evolution of complex traits using whole-genome genealogiesR35GM150579 · NIGMS · CORNELL UNIVERSITY · PI Xinzhu Wei · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150579
6 · The paper itself

Abstract

Motivation: The Genotype Representation Graph (GRG) is a graph representation of whole genome polymorphisms, designed to encode the variant hard-call information in phased whole genomes. It encodes the genotypes as an extremely compact graph that can be traversed efficiently, enabling dynamic programming-style algorithms on applications such as genome-wide association studies that run faster on biobank-scale data than existing alternatives. To facilitate scalable statistical genetics, we present Results: Availability and implementation: The

Indexed as

BioinformaticsPhenotypeSimulatorSoftwareStatistical Genetics

Identifiers

PMID41736997
PMCPMC12927419

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.