Evidence map›Paper›PMID 41737131›Full record

ArticleCurrent opinion in physiology2026

Recent insights into the immunobiology of congenital cytomegalovirus infection.

Elizabeth Ann L Enninga, Mark R Schleiss, Craig J Bierle

Abstract read
In one paragraph

Article in Current opinion in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth Ann L EnningaDepartment of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN USA.ORCID 0000-0003-3621-7335
Mark R SchleissDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Minnesota, Minneapolis, MN USA.ORCID 0000-0002-2108-9433
Craig J BierleDivision of Pediatric Infectious Diseases, Department of Pediatrics, University of Minnesota, Minneapolis, MN USA.ORCID 0000-0002-7890-7409

Funding

Optimizing Immunity and Maternal Host Defense Against Congenital Cytomegalovirus InfectionR01HD098866 · NICHD · UNIVERSITY OF MINNESOTA · PI Craig John Bierle, Michael A McVoy · 2019 to 2026
$3.9M
Trophoblast development and placental susceptibility to cytomegalovirus infectionR01HD109252 · NICHD · UNIVERSITY OF MINNESOTA · PI Craig John Bierle · 2022 to 2026
$2.2M
Defining T cell-placenta immune mechanisms in chronic villitisR56AI177472 · NIAID · MAYO CLINIC ROCHESTER · PI ENNINGA, ELIZABETH ANN LIESER · 2024 to 2024
$326k
NIAID NIH HHS R56 AI177472NICHD NIH HHS R01 HD098866NICHD NIH HHS R01 HD109252
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and therapeutic interventions remain limited. This review highlights recent findings on the immunobiology of HCMV during pregnancy, exploring the roles of maternal and fetal/neonatal T cell responses in controlling infection. The utility of

Indexed as

cytomegalovirusimmunityplacentapregnancytrophoblasts

Identifiers

PMID41737131
PMCPMC12927654

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.