Evidence map›Paper›PMID 41737462›Full record

ArticleMaterials today. Bio2026

3D-printed PRP-infused double-network hydrogels orchestrate inflammation resolution and vascular regeneration in infected wounds.

Danlei Xing, Zhiyuan Hu, Yue Tao, Hang Xia, Juanjuan Li, Guoqing Xia, Le Qiu, Jie Shan, Xiaojun Zha, Xu-Lin Chen

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danlei XingDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Zhiyuan HuDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Yue TaoDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Hang XiaDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Juanjuan LiDepartment of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, PR China.
Guoqing XiaInstitute for Liver Diseases of Anhui Medical University, The Key Laboratory of Anti-inflammatory and Immune Medicines, Ministry of Education, Hefei, 230032, PR China.
Le QiuDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Jie ShanDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.
Xiaojun ZhaDepartment of Biochemistry & Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, 230032, PR China.
Xu-Lin ChenDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infection and excessive inflammation critically impede wound healing, necessitating the development of multifunctional bioactive materials. Herein, we report a biodegradable composite hydrogel (PPG) fabricated via projection-based 3D biophotocuring, comprising an interpenetrating double-network of gelatin methacryloyl (GelMA) and poly-L-lysine methacryloyl (PLMA), embedded with platelet-rich plasma (PRP). The resulting hydrogel exhibits potent antibacterial activity and robust inhibition of biofilm formation, alongside integrated anti-inflammatory and pro-angiogenic functions.

Indexed as

3D printingAngiogenesisAntibacterialHydrogelInfected wound healing

Identifiers

PMID41737462
PMCPMC12927089

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.