Evidence map›Paper›PMID 41737484›Full record

ArticleFrontiers in oncology2026

Knowledge, attitudes, and decision-making regarding hyperbaric oxygen-assisted cancer treatment among related healthcare professionals.

Cheng Zhou, Jia Zhang, Zhengze Dai, Dalin Fu, Yi Sun, Guopei Wu, Linsheng Chen, Xiao Lu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheng ZhouDepartment of Rehabilitation, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, School of Rehabilitation Medicine, Nanjing Medical University, Nanjing, China.
Jia ZhangDepartment of Nursing of Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
Zhengze DaiDepartment of Neurology, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Dalin FuDepartment of Rehabilitation, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Yi SunDepartment of Rehabilitation, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, School of Rehabilitation Medicine, Nanjing Medical University, Nanjing, China.
Guopei WuDepartment of Rehabilitation Medicine, Nantong Rici Hospital Affiliated to Yangzhou University, Nantong, Jiangsu, China.
Linsheng ChenDepartment of Rehabilitation, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, School of Rehabilitation Medicine, Nanjing Medical University, Nanjing, China.
Xiao LuDepartment of Rehabilitation, Jiangsu Province People's Hospital and Nanjing Medical University First Affiliated Hospital, School of Rehabilitation Medicine, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: This study aimed to evaluate the knowledge, attitudes, and clinical decision-making of healthcare professionals in hyperbaric oxygen therapy (HBOT) units and oncology specialties regarding HBOT as an adjunctive cancer treatment. Methods: A cross-sectional survey was conducted between February, 2024 and February, 2025. Data were collected using a structured questionnaire, which included sections on demographic characteristics and assessed participants' knowledge, attitudes, and practices (KAP) related to hyperbaric oxygen-assisted cancer therapy. The KAP scores were calculated to quantify the respondents' familiarity with and perspectives on the treatment. Results: Of 202 valid questionnaires, 58.91% were physicians. The majority (63.86%) had over 15 years of clinical experience, and 79.70% reported prior HBOT training in oncology. The mean scores were 52.87 ± 12.21 for knowledge, 41.24 ± 5.92 for attitudes, and 22.40 ± 2.38 for decision-making. Analysis indicated that knowledge positively influenced attitudes (β=0.393, P = 0.013) and decision-making (β = 0.159, P = 0.018), while attitudes significantly impacted decision-making (β = 0.318, P = 0.012). Knowledge indirectly affected decision-making via attitude (β = 0.125, P = 0.004). Conclusions: Healthcare professionals working in HBOT units and oncology-related specialties demonstrated a generally adequate level of knowledge, positive attitudes, and a proactive approach toward the use of HBOT as an adjunctive cancer treatment, with attitude emerging as a key mediator linking knowledge to clinical decision-making. These findings highlight the importance of targeted educational interventions aimed at strengthening both knowledge and attitudes, which may in turn enhance evidence-based clinical decision-making and support the broader integration of HBOT into oncologic care pathways.

Indexed as

attitudecross-sectional studydecision makinghyperbaric oxygenationknowledgeneoplasmspractice

Identifiers

PMID41737484
PMCPMC12926112

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.