Evidence mapPaperPMID 41737728Full record

SynthesisFrontiers in psychiatry2025

Scoping review of precision child and youth mental health research: dwelling in possibility.

Joonsoo Sean Lyeo, Angelica Blais, Paula Cloutier, Addo Boafo, Aroldo Dargél, Amanda Helleman, Tanya Tanya, Esperance Kashala-Abotnes, Christina Honeywell, Kathleen Pajer

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joonsoo Sean LyeoChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Angelica BlaisChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Paula CloutierChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Addo BoafoChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Aroldo DargélDepartment of Psychiatry, University of Ottawa Medical School, Ottawa, ON, Canada.
Amanda HellemanChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Tanya TanyaThe Ottawa Hospital, Ottawa, ON, Canada.
Esperance Kashala-AbotnesChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Christina HoneywellChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Kathleen PajerChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Precision child and youth mental health (PCYMH) offers a promising array of tools and methodologies to address the intensifying burden of mental health challenges in child and youth populations. However, the current state of PCYMH research requires better characterization. To this end, we conducted a scoping review aiming to provide a 'lay of the literature' for this emerging field. Methods: Following the Joanna Briggs Institute methodology for scoping reviews, we searched PubMed and Embase for PCYMH studies from January 1, 1980 to November 30, 2023, updating the search on November 1, 2024. The final dataset comprised 124 publications, summarized with descriptive quantitative analysis and qualitative content analysis. Results: Quantitative analyses revealed that 48% (60/124) of studies had been published between 2020 and 2024, with the majority (51% (63/124)) studying populations in the U.S. Most studies were observational in design. Content analysis revealed four categories of PCYMH research focus: (1) Biomarkers (68% (84/124)); (2) Non-Biological Markers (17% (22/124)); (3) Implementation of PCYMH Interventions (14% (17/124)); and (4) Predictive Algorithms (5% (6/124)). PCYMH tools were underutilized and infrequently combined. Studies producing multimodal profiles of participants, e.g., using neuroimaging, genetics, digital health data, and lifestyle data were scarce. No study used reporting guidelines. Discussion: Our findings indicate that this body of research is still in its infancy. We highlight opportunities to advance the study of PCYMH and provide recommendations to support the maturation of this new field.

Indexed as

adolescentschildrenprecision behavioural healthprecision mental healthprecision psychiatryyouth

Identifiers

PMID41737728
PMCPMC12926772

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.