Evidence map›Paper›PMID 41738012›Full record

ArticleImaging neuroscience (Cambridge, Mass.)

Detecting short-interval longitudinal cortical atrophy in neurodegenerative dementias via cluster scanning: A proof of concept.

Yuta Katsumi, Michael Brickhouse, Lindsay C Hanford, Jared A Nielsen, Maxwell L Elliott, Ross W Mair, Alexandra Touroutoglou, Mark C Eldaief, Randy L Buckner, Bradford C Dickerson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Yuta KatsumiFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.ORCID https://orcid.org/0000-0003-0413-747X
Michael BrickhouseFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Lindsay C HanfordDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA, United States.
Jared A NielsenDepartment of Psychology, Neuroscience Center, Brigham Young University, Provo, UT, United States.ORCID https://orcid.org/0000-0002-2717-193X
Maxwell L ElliottDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA, United States.
Ross W MairDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA, United States.
Alexandra TouroutoglouFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Mark C EldaiefFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Randy L BucknerDepartment of Psychology, Center for Brain Science, Harvard University, Cambridge, MA, United States.
Bradford C DickersonFrontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

Funding

Neurogenetic contributions to the spread of tau pathology in sporadic early-onset Alzheimer's diseaseK01AG084820 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Yuta Katsumi · 2024 to 2026
$387k
NIA NIH HHS K01 AG084820
6 · The paper itself

Abstract

Regional brain atrophy estimated from structural magnetic resonance imaging (MRI) is a widely used measure of neurodegeneration in Alzheimer's disease (AD), Frontotemporal Lobar Degeneration (FTLD), and other dementias. Yet, traditional MRI-derived morphometric estimates are susceptible to measurement errors, posing a challenge for detecting longitudinal atrophy over short intervals. Here, we examined the utility of multiple MRI scans acquired in rapid succession (i.e.,

Indexed as

Alzheimer’s diseasecortical thicknessfrontotemporal lobar degenerationmagnetic resonance imagingprecision neuroimaging

Identifiers

PMID41738012
PMCPMC12926775

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.