Evidence map›Paper›PMID 41739167›Full record

Trial reportEuropean journal of applied physiology2026

Effects of different exercise training programs on post-exercise [Formula: see text]O

Mathieu Gayda, Lukas-Daniel Trachsel, Florent Besnier, Maxime Boidin, Julie Lalongé, Louis Bherer, Martin Juneau, Pierre-Marie Leprêtre, Anil Nigam

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02048696 nacompletednot on this map

Effect of Exercise Training on Left Ventricular Function in Patients Post Myocardial Infarction: The EXercise Interval Training - V Study

TypeinterventionalSponsorMontreal Heart InstituteRan2014 to 2018Enrolled26ConditionsMyocardial Infarction, Heart Failure, Coronary Artery DiseaseArmsSecondary prevention and cardiac rehabilitation clinic
NCT03414996 nacompletednot on this map

The Effects of High-intensity Interval Training on Maximal Oxygen Uptake and Autonomic Nervous System in Patients With Post-acute Coronary Syndrome

TypeinterventionalSponsorMontreal Heart InstituteRan2011 to 2021Enrolled60ConditionsAcute Coronary Syndrome, ArrhythmiaArmsExercise training
NCT03443193 nacompletednot on this map

The Effects of Periodization Training on Physiological Parameters, Cerebral Oxygenation, Cognitive Functions and Cardiac Remodelling in Coronary Patients.

TypeinterventionalSponsorMontreal Heart InstituteRan2015 to 2021Enrolled70ConditionsCoronary Heart Disease, Healthy ControlArmsExercise training
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mathieu GaydaPreventive Medicine and Physical Activity (ÉPIC) Center, Montreal Heart Institute, 5055 St Zotique Street East, Montreal, QC, H1T 1N6, Canada. mathieu.gayda@icm-mhi.org.ORCID http://orcid.org/0000-0003-1721-2299
Lukas-Daniel TrachselUniversity Clinic for Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-0994-5425
Florent BesnierUniversité Paris Cité, Institut Des Sciences du Sport-Santé de Paris, 75015, Paris, France.ORCID http://orcid.org/0000-0003-0835-9483
Maxime BoidinResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.
Julie LalongéPreventive Medicine and Physical Activity (ÉPIC) Center, Montreal Heart Institute, 5055 St Zotique Street East, Montreal, QC, H1T 1N6, Canada.
Louis BhererPreventive Medicine and Physical Activity (ÉPIC) Center, Montreal Heart Institute, 5055 St Zotique Street East, Montreal, QC, H1T 1N6, Canada.ORCID https://orcid.org/0000-0003-2258-8194
Martin JuneauPreventive Medicine and Physical Activity (ÉPIC) Center, Montreal Heart Institute, 5055 St Zotique Street East, Montreal, QC, H1T 1N6, Canada.
Pierre-Marie LeprêtreUniv Rouen Normandie, Normandie Univ, CETAPS UR 3882, Rouen, France.ORCID https://orcid.org/0000-0002-5149-2768
Anil NigamPreventive Medicine and Physical Activity (ÉPIC) Center, Montreal Heart Institute, 5055 St Zotique Street East, Montreal, QC, H1T 1N6, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOxygen deficit (O2 deficit) and post-exercise oxygen uptake ([Formula: see text]O2) recovery responses are clinical prognostic markers in cardiac patients but have not been studied after exercise training in patients with coronary heart disease (CHD). We aimed to compare the effects of different modalities of exercise training on O2 deficit and post-exercise [Formula: see text]O2 responses in CHD patients.

methodsFrom a pooled analysis of three randomised control trial, patients with CHD were trained with moderate-intensity continuous exercise training (MICET), low volume high-intensity interval training (LV-HIIT), or combined MICET/HIIT for 12 weeks. Cardiopulmonary exercise test (CPET) parameters were assessed, and key exercise variables were calculated during and after exercise. O2 deficit, CPET post-exercise kinetics time constant for oxygen uptake ([Formula: see text]O2), carbon dioxide ([Formula: see text]CO2), minute ventilation ([Formula: see text]E) and heart rate (τHR), O2 debt and [Formula: see text]O2 recovery delay (RD) were calculated before and after training.

resultsA significant training effect for [Formula: see text]O2 (p < 0.05) was shown for all groups. Shorter [Formula: see text]O2 values with small effect size (ES from 0.21 to 0.4) were noted for the combined MICET/HIIT and MICET groups. A significant training effect (p < 0.01) was noted for O2 debt that was increased after training (ES: 0.1 to 0.47). No significant statistical effect was shown for [Formula: see text]O2 RD and [Formula: see text]CO2, [Formula: see text]E, τHR and O2 deficit in all groups.

conclusionsIn patients with CHD, exercise training improved post-exercise [Formula: see text]O2 kinetic and the O2 debt, with a higher impact of exercise dose (combined MICET/HIIT). Exercise training did not improve the [Formula: see text]O2 RD or the recovery time constant value of other cardiorespiratory parameters in CHD patients.

trial registrationNCT03414996, NCT02048696, NCT03443193.

Indexed as

Coronary DiseaseExercise TherapyOxygen ConsumptionAgedExercise TestFemaleHeart RateHigh-Intensity Interval TrainingHumansMaleMiddle AgedPost-Exercise RecoveryContinuous exercise trainingCoronary heart diseaseHigh-intensity interval trainingPost-exercise [Formula: see text]O2 kineticsRecovery

Identifiers

PMID41739167

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.