Evidence map›Paper›PMID 41739996›Full record

ArticleHuman reproduction (Oxford, England)2026

The problem with the 'truth': rethinking ground truth for artificial intelligence in endometriosis diagnosis.

Alison Deslandes, Yuan Zhang, Mathew Leonardi, Hsiang-Ting Chen, Gustavo Carneiro, Jodie Avery, George Condous, Steven Knox, M Louise Hull, IMAGENDO Team

Abstract read
In one paragraph

Article in Human reproduction (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alison DeslandesRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0001-7094-3950
Yuan ZhangRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0002-3484-3140
Mathew LeonardiRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0001-5538-6906
Hsiang-Ting ChenSchool of Computer and Mathematical Sciences, University of Adelaide, Adelaide, Australia.
Gustavo CarneiroCentre for Vision, Speech and Signal Processing (CVSSP), University of Surrey, Guildford, United Kingdom.
Jodie AveryRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0002-8857-9162
George CondousRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0003-3858-3080
Steven KnoxBenson Radiology, Adelaide, Australia.ORCID 0009-0007-6509-8634
M Louise HullRobinson Research Institute, University of Adelaide, Adelaide, Australia.ORCID 0000-0003-1813-3971
IMAGENDO Team

Funding

Australian Government through the Medical Research Futures Fund: Primary Health Care Research Data Infrastructure Grant 2020Endometriosis AustraliaMedical Research Futures Fund: Primary Health Care Research Data Infrastructure 2020NHMRC 2024
6 · The paper itself

Abstract

Artificial intelligence (AI) is revolutionizing how we practice medicine. In areas where we have traditionally struggled, such as diagnosing endometriosis, AI has significant potential to improve the breadth and accuracy of diagnostic services offering a great benefit to patient care. When developing AI models for diagnosis, the 'ground truth' refers to the reference standard used in the labelling of the data used to train the model. Conventionally, in clinical medicine, we correlate any new diagnostic tool to the established 'gold standard', which in the case of endometriosis is laparoscopic visualization of lesions and histological confirmation. This method however is increasingly recognized as imperfect. Acknowledgement of the limitations of surgery and recent improvements in the diagnostic capability of imaging technologies to detect endometriosis, has created a situation where endometriosis no longer has one clear 'gold standard' for diagnosis. In this commentary, we will explore the impact of this on AI-driven endometriosis diagnostic tools and propose novel ways this could be addressed in the context of creating ground truths for endometriosis diagnosis.

Indexed as

Artificial IntelligenceEndometriosisFemaleHumansLaparoscopyUltrasonographyartificial intelligenceendometriosisgynaecologymachine learningMRIsurgeryultrasound

Identifiers

PMID41739996
PMCPMC13139653

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.