Evidence map›Paper›PMID 41740620›Full record

ArticleCurrent opinion in obstetrics & gynecology2026

Stimulating discussion: neuromodulation for migraine in pregnancy.

Gregory A Panza, Michele Godorecci, Michael A L Johnson, Deena E Kuruvilla, Jolene Seibel-Seamon

Abstract read
In one paragraph

Article in Current opinion in obstetrics & gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gregory A PanzaDepartment of Research, Hartford Healthcare, Hartford, Connecticut.
Michele GodorecciObstetrics and Gynecology Department, Advocare, The OB/GYN Specialists.
Michael A L JohnsonDepartment of Medical Affairs, Cefaly Technology, Seraing, Belgium.
Deena E KuruvillaBrain Health Institute, Westport, Connecticut.
Jolene Seibel-SeamonMaternal and Fetal Medicine, Virtua Medical Group, Voorhees, New Jersey, USA.

Funding

Cefaly Technology
6 · The paper itself

Abstract

purpose of reviewNoninvasive neuromodulation is a promising nonpharmaceutical option in migraine treatment during pregnancy due to its well-established safety and efficacy profile in the general population and versatility as adjunctive/alternative therapy to medication. We discuss: the current pivotal trials on neuromodulation for migraine treatment in general and pregnancy populations, why neuromodulation may be unknown and underutilized among clinicians, and neuromodulation's future for migraine in pregnancy. RECENT

findingsEvidence for neuromodulation use during pregnancy is limited, especially for migraine treatment. Contributing factors include the exclusion of pregnant women with migraine from clinical trials, the lack of nonpharmaceutical use data in epidemiological studies, and limited research funding. Evidence can be improved through advocacy by professional organizations, systemic funding, and increased patient awareness. Limited clinician knowledge, awareness, and access may contribute to underutilization. Education, insurance coverage advocacy, and multidisciplinary approaches to migraine treatment in pregnancy are needed. SUMMARY: Neuromodulation may already represent a clinically meaningful nonpharmacologic alternative for treating migraine during pregnancy. Neuromodulation offers precision therapy, clinical data tracking, and the potential to treat multiple pregnancy health conditions. Despite its safety potential, it remains underutilized. Increased research, clinician education, and multidisciplinary care could support broader adoption.

Indexed as

headachemigraineneuromodulationnonpharmaceuticalpregnancy

Identifiers

PMID41740620
PMCPMC12931871

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.