Evidence map›Paper›PMID 41740658›Full record

ArticleMagnetic resonance imaging2026

Diffusion MRI measures detect brain microstructure changes due to early treatment with neurotrophic peptide mimetic P021 in the 3xTg-AD mouse model of Alzheimer's disease.

M F Falangola, J Voltin, M Cole, P J Nietert, F Liu, K Iqbal, J H Jensen

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

M F FalangolaDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, USA. Electronic address: falangol@musc.edu.
J VoltinDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, USA.
M ColeDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA.
P J NietertDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.
F LiuDepartment of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
K IqbalDepartment of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
J H JensenDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC, USA; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, USA; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, SC, USA.

Funding

Diffusion and Functional MRI Monitoring of Therapy Response in Alzheimer’s Disease Mouse ModelR01AG057602 · NIA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MARIA F FALANGOLA, JENS H JENSEN · 2023 to 2026
$2.7M
NIA NIH HHS R01 AG057602
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3xTg-ADAlzheimer's diseaseDiffusional kurtosis imagingDiffusion MRINeurodegenerative diseasesNeurotrophic peptidergic compound P021White matter pathology

Identifiers

PMID41740658
PMCPMC12993872

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.