ArticleAmerican journal of human biology : the official journal of the Human Biology Council2026
Effect of Using the Food Quotient as a Proxy of the Respiratory Quotient in the Calculation of Energy Expenditure by the Doubly Labeled Water Method in Older Adults.
Article in American journal of human biology : the official journal of the Human Biology Council, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
aimsAccurate measurement of total energy expenditure (TEE) is critical for maintaining energy balance and body weight. This study aimed to analyze differences in TEE assessed by the doubly labeled water method (DLW-TEE), using food quotient (FQ) derived from self-reported 24-h dietary recalls, respiratory quotient measured by indirect calorimetry (RQ-IC), and usual respiratory quotient of 0.85 (RQ-0.85) based on Western-type diet intakes.
methodsSecondary analysis from a cross-sectional study conducted in a sample of 41 independent (21 women) older people (≥ 60 years). FQ was obtained from three self-reported 24-h dietary recalls, RQ-IC was measured after an overnight fast under resting conditions. Repeated measures analysis of variance was used to compare differences in DLW-TEE calculated with FQ, RQ-IC, and RQ-0.85.
resultsDLW-TEE was significantly different between the three approaches (p = 0.025). The RQ approaches on DLW-TEE did not differ significantly between sexes (p = 0.325). The overall mean DLW-TEE RQ-0.85 was 2253 (SD = 529, 95% CI: 2086, 2420) kcal/day, DLW-TEE RQ-IC was 2251 (SD = 541, 95% CI 2090, 2431) kcal/day, and DLW-TEE FQ was 2208 (SD = 534, 95% CI 2039, 2376). DLW-TEE calculated with FQ significantly reduced TEE compared to the mean DLW-TEE with RQ-0.85 values (ΔTEE -45 kcal/day, p < 0.001).
conclusionSelf-reported dietary intake data may provide a more context-specific estimate of the FQ than relying solely on RQ from indirect calorimetry or the fixed RQ of 0.85 in DLW-based TEE calculations. Although the resulting differences in TEE are modest, they can lead to overestimation of energy requirements over time.
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