Evidence map›Paper›PMID 41741681›Full record

ReviewNature ecology & evolution2026

The molecular evolution of vertebrate organs.

Margarida Cardoso-Moreira

Abstract readReview
In one paragraph

Review in Nature ecology & evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Margarida Cardoso-MoreiraEvolutionary Developmental Biology Laboratory, The Francis Crick Institute, London, UK. margarida.cardosomoreira@crick.ac.uk.ORCID http://orcid.org/0000-0001-6639-3597

Funding

Wellcome Trust CC2185
6 · The paper itself

Abstract

The ecological and evolutionary success of vertebrates stems in large part from their remarkably diverse organs. Understanding how this organ diversity has arisen has been a long-standing goal. What molecular and developmental changes are responsible for the origin and diversification of vertebrate organs, and what evolutionary forces drove these changes? This Review discusses major leaps in our understanding of the molecular evolution of vertebrate organs made possible by technological advances-that is, whole-genome sequencing, functional and single-cell genomics, and genome editing tools. I summarize how organs and cell types evolve at different rates, and the distinct contributions that some types of molecular change make to organ evolution. Finally, I discuss how new, complex traits evolve-from cells to tissues and organs-and how these innovations have fuelled the diversification of vertebrates.

Indexed as

Evolution, MolecularVertebratesAnimals

Identifiers

PMID41741681
PMCPMC7618898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.