Evidence map›Paper›PMID 41742039›Full record

ArticleBMC infectious diseases2026

Lacticaseibacillus paracasei bacteremia and mediastinitis secondary to esophageal invasion by left hilar pleomorphic carcinoma: case report.

Natsumi Kushima, Toyoshi Yanagihara, Kaori Koga, Takashi Asahara, Shuta Yamamoto, Yuki Shundo, Naoki Hamada, Makoto Hamasaki, Masaki Fujita

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natsumi KushimaDepartment of Respiratory Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Toyoshi YanagiharaDepartment of Respiratory Medicine, Fukuoka University Hospital, Fukuoka, Japan. toyoshi.yana@fukuoka-u.ac.jp.
Kaori KogaDepartment of Pathology, Fukuoka University School of Medicine, Fukuoka, Japan.
Takashi AsaharaYakult Central Institute, Yakult Honsha Co., Ltd, Tokyo, Japan.
Shuta YamamotoYakult Central Institute, Yakult Honsha Co., Ltd, Tokyo, Japan.
Yuki ShundoDepartment of Respiratory Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Naoki HamadaDepartment of Respiratory Medicine, Fukuoka University Hospital, Fukuoka, Japan.
Makoto HamasakiDepartment of Pathology, Fukuoka University School of Medicine, Fukuoka, Japan.
Masaki FujitaDepartment of Respiratory Medicine, Fukuoka University Hospital, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lacticaseibacillus paracasei bacteremia associated with probiotic use is rare. We report a 71-year-old man with advanced lung cancer who developed L. paracasei bacteremia while ingesting a commercially available probiotic-fermented milk. Autopsy demonstrated direct tumor invasion and perforation of the mid-esophagus, providing a structural route for bacterial translocation from the gastrointestinal lumen into the bloodstream. Genetic analysis showed that the blood isolate was genetically identical to the probiotic strain contained in the ingested product. Bacteremia resolved with antibiotics, but the patient died of respiratory failure from progression of the malignancy. This case highlights that probiotic organisms, despite an established safety profile, can cause bacteremia when immunocompromise coexists with disruption of the gastrointestinal barrier.

Indexed as

BacteremiaGram-Positive Bacterial InfectionsLacticaseibacillus paracaseiLung NeoplasmsMediastinitisProbioticsAgedAnti-Bacterial AgentsFatal OutcomeHumansMaleAnti-Bacterial AgentsBacteremiaBacterial translocationCase reportsLacticaseibacillus paracaseiLung neoplasmMediastinitisProbiotics

Identifiers

PMID41742039
PMCPMC13041003

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.