Evidence map›Paper›PMID 41742133›Full record

Trial reportBMC endocrine disorders2026

The effect of dietary approaches to stop hypertension (DASH) diet on cardiometabolic and atherogenic indices in subjects with metabolic syndrome: a randomized clinical trial.

Xun Wei, Alireza Takzare, Rafat Rezapour-Nasrabad, Abbas Ali Sangouni, Mahdieh Hosseinzadeh, Karim Parastouei

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC endocrine disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xun WeiRuikang Hospital, Guangxi University of Chinese Medicine, Nanning, China.
Alireza TakzareAnaesthesiology Department, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Rafat Rezapour-NasrabadSchool of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abbas Ali SangouniDepartment of Nutrition and Food Hygiene, Faculty of Health, Baqiyatallah University of Medical Sciences, PO Box: 1435915371, Tehran, Iran.
Mahdieh HosseinzadehDepartment of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Karim ParastoueiDepartment of Nutrition and Food Hygiene, Faculty of Health, Baqiyatallah University of Medical Sciences, PO Box: 1435915371, Tehran, Iran. parastouei@gmail.com.ORCID http://orcid.org/0000-0002-8087-663X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary approaches to stop hypertension (DASH) diet as a balanced dietary pattern is designed to help manage hypertension. The scientific evidence hypothesized that following the DASH diet may lead to reductions in cardiometabolic risk. We aimed to design a clinical trial to assess the impact of the DASH diet on cardiometabolic and atherogenic indices in individuals with metabolic syndrome (MetS).

methodsSixty participants diagnosed with MetS were randomly divided into two groups: the intervention group (adhering to DASH diet) or the control group (following a common healthy diet). Key outcomes of the present study including cardiometabolic index (CMI) as our primary outcome, and atherogenic index of plasma (AIP), atherogenic coefficient (AC) and castelli risk index II (CRI-II) as secondary outcomes were evaluated at the baseline and at the end of the study.

resultsWhile one participant excluded from the trial, 59 subjects completed the study. Baseline values of CMI (p = 0.33), AIP (p = 0.27), AC (p = 0.44) and CRI-II (p = 0.17) showed no significant difference between the intervention group and the control group. After adjusting for confounding factors, the intervention group demonstrated a significant decrease compared to the control group in CMI (−0.38±0.29 vs. −0.02±0.47; p = 0.001), AIP (−0.04±0.04 vs. 0.01 ± 0.07; p = 0.001), AC (−0.31±0.54 vs. 0.01 ± 0.72; p = 0.04) and CRI-II (−0.30±0.37 vs. −0.03±0.39; p = 0.009).

conclusionsAdherence to the DASH diet appears to be effective in reducing CMI and some atherogenic indices. Further well-designed clinical trials with longer intervention durations are needed.

trial registrationThe trial was registered on 21 October 2022 at Iranian Registry of Clinical Trials (IRCT20180201038585N12, https://irct.behdasht.gov.ir/trial/66161 ).

Indexed as

AtherosclerosisDietary Approaches To Stop HypertensionHypertensionMetabolic SyndromeAdultCardiometabolic Risk FactorsFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisCardiometabolic riskDASH dietMetabolic syndrome

Identifiers

PMID41742133
PMCPMC13041230

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.