Evidence map›Paper›PMID 41742513›Full record

ArticleJournal of veterinary internal medicine2026

Treatment outcomes and prognostic indicators of primary immune thrombocytopenia in 31 cats: a multicenter retrospective study (2000-2023).

Mulan Zhong, Evelyn Hall, Barbara Glanemann, Susan H S Jih, Rachel M Korman, Rebecca Langhorn, Jana Leshinsky, Amy E Lingard, Elodie Roels, Martine van Boeijen and 1 more

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Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Mulan ZhongSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, New South Wales 2006, Australia.
Evelyn HallSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, New South Wales 2006, Australia.
Barbara GlanemannQueen Mother Hospital for Animals, The Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom.
Susan H S JihThe Cat Clinic, Brisbane, Queensland, Australia.
Rachel M KormanVeterinary Specialist Services, Brisbane, Queensland, Australia.
Rebecca LanghornDepartment of Veterinary Clinical Sciences, University of Copenhagen, Frederiksberg, Denmark.
Jana LeshinskySmall Animal Specialist Hospital, Ryde, New South Wales, Australia.
Amy E LingardThe Cat Doctors, Melbourne, Victoria, Australia.
Elodie RoelsDepartment of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
Martine van BoeijenPerth Cat Hospital, Perth, Western Australia, Australia.
Lara A BolandSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Sydney, New South Wales 2006, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary immune thrombocytopenia (ITP) in cats is rare. Evidence is lacking on effective immunosuppressive protocols, prognosis, and prognostic indicators. HYPOTHESIS/

objectivesTo investigate immunosuppressive treatment outcomes and prognostic indicators of cats with primary ITP. ANIMALS: Thirty-one cats with primary ITP.

methodsMulti-institutional retrospective cohort study (2000-2023). Cats were identified by searching medical records from 12 institutions. Immunosuppressive treatments and prognostic indicators were studied in association with clinical outcomes. Indicators included age, sex, breed, bodyweight, initial platelet count and PCV, blood urea nitrogen concentration, and blood product administration. Outcomes including medical control (platelet count > 57 000/μL), relapse, remission, death, and survival to discharge were analyzed using logistic regression models. Hospitalization duration, days to medical control, remission, and death were assessed using linear regression models. Survival was assessed using the Kaplan-Meier method.

resultsOf the cats included, 27/31 (87%) survived to discharge, 25/31 (81%) achieved medical control, 8/25 (32%) achieved remission, 10/25 (40%) relapsed during immunosuppressive tapering, and 5/10 (50%) had a second relapse. Cats administered corticosteroids and cyclosporine had longer hospitalizations than corticosteroids alone (8.4 ± 0.9 vs 4.4 ± 0.9 days; P = .005). Median survival was not reached. Median follow-up was 315 days (95% CI, 216-1252). CONCLUSIONS AND CLINICAL IMPORTANCE: Cats with primary ITP have a fair short-term prognosis and low remission rate. The frequent relapse rate warrants close monitoring. Besides longer hospitalization durations, combination immunosuppressive treatment did not affect other outcomes, when compared to corticosteroids alone.

Indexed as

autoimmunefelineplateletthrombocytopenic

Identifiers

PMID41742513
PMCPMC13147439

What Socratic holds

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