Evidence map›Paper›PMID 41743077›Full record

ArticleClinical and experimental gastroenterology2026

Development and Validation of a Postoperative Delirium Prediction Model for Patients Undergoing Gastrointestinal Surgery.

Zhihua Huang, Yang Deng, Qiang Li, Tianran Hu, Xiaoying Xu, Yan Luo

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Article in Clinical and experimental gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhihua Huang *Department of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.ORCID 0000-0002-3428-502X
Yang Deng *Department of Gastrointestinal Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Qiang LiDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Tianran HuDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Xiaoying XuDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Yan LuoDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.ORCID 0000-0003-0431-3162

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative delirium (POD) is a critical and prevalent postoperative complication challenging to major surgeries, associated with the increased morbidity and mortality rate, prolonged hospitalization, and higher healthcare expenditure. Despite the availability of POD prediction tools, none of the models deals particularly with the unique preoperative risks of gastrointestinal surgery patients, which is the critical gap in the present clinical practice. Thus, the objectives of the study were the development and validation of an easy-to-use preoperative prediction model for POD specifically for patients undergoing gastrointestinal surgery, to narrow this gap by a specific population tool. Methods: A total of 369 patients undergoing gastrointestinal surgery were analyzed retrospectively. Univariate analysis was used to identify candidate variables, and a multivariate logistic regression model was built using with statistically significant predictors (P<0.05). The area under the receiver operating characteristic curve (AUC) was used as a measure of model performance. Internal validation was done though 20 times 5-fold cross-validation of the models as a measure of robustness. Results: Univariate analysis identified four statistically significant factors for POD: advanced age (OR = 4.19, 95% CI: 1.68-11.91), lower educational level (OR = 0.25, 95% CI: 0.10-0.60), history of cerebrovascular disease (OR = 6.59, 95% CI: 2.55-16.47), and elevated preoperative serum glucose level (OR = 2.68, 95% CI: 1.03-6.54). All these factors were included in the final POD prediction model, which proved to have strong discriminative power (AUC = 0.810, 95% CI: 0.700-0.921) and good calibration (Hosmer-Lemeshow test, P = 0.436). Conclusion: This model is the first easy-to-use preoperative prediction model of POD particularly developed for gastrointestinal surgical patients and exhibits high discriminatory accuracy. It enables anesthesiologists to promptly stratify the risk of POD, which will allow them to implement preventive interventions in time.

Indexed as

gastrointestinal surgerynomogrampostoperative deliriumprediction modelrisk factors

Identifiers

PMID41743077
PMCPMC12931139

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.