Evidence mapPaperPMID 41743402Full record

ArticleCurrent pediatrics reports2025

Metabolic Implications of PCOS.

Amna Naveed, Rachana Shah, Angelina Bernier, Valeriia Muradova, Eray Savgan Gurol, Melanie Cree, Rachel Whooten

Abstract read
In one paragraph

Article in Current pediatrics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amna NaveedDivision of Pediatric Endocrinology, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, MA 02114, USA.
Rachana ShahDivision of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Angelina BernierDivision of Pediatric Endocrinology, UF Health Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32608, USA.
Valeriia MuradovaDivision of Pediatric Endocrinology, UF Health Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32608, USA.
Eray Savgan GurolDivision of Pediatric Endocrinology, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, MA 02114, USA.
Melanie CreeDivision of Pediatric Endocrinology, University of Colorado Anschutz, Aurora, CO 80045, USA.
Rachel WhootenDivision of Pediatric Endocrinology, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, MA 02114, USA.

Funding

Investigating the impact of physical activity in modulating PCOS risk among peripubertal femalesK23DK131322 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · 2024 to 2025
$384k
NIDDK NIH HHS K23 DK131322
6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine condition among women, with associated cardiometabolic comorbidities. While there are limitations to both the diagnosis of PCOS and cardiometabolic disease within adolescence, there is evidence that adolescents with PCOS have greater risk for insulin resistance, cardiovascular and adipose tissue dysfunction, and hepatic steatosis. This review aims to explore the risk of metabolic disease in adolescents with PCOS and its association with disease phenotypes, offering insight into the evolution of this metabolic risk into adulthood. These findings reinforce the critical need for timely diagnosis of PCOS, combined with targeted lifestyle interventions, to mitigate cardiometabolic risk and shift the trajectory of long-term health outcomes.

Indexed as

AdiposityAdolescentsCardiometabolic RiskHepatic SteatosisInsulin ResistancePolycystic Ovary Syndrome

Identifiers

PMID41743402
PMCPMC12931838

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.