ReviewFrontiers in medicine2025
Effects of acupuncture and moxibustion therapy on endometrial receptivity of infertile women with
Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Objective: This study aims to comprehensively synthesize recent advances in acupuncture and moxibustion for enhancing ER in IVF-ET patients, promoting clinical application and research awareness. Methods: A systematic literature search was conducted across PubMed, Web of Science, CNKI, and WanFang databases (January 2020-June 2025), supplemented with seminal studies. After screening, 214 studies were included for qualitative synthesis; methodological quality was assessed using RoB 2.0 (RCTs) and NOS (non-RCTs). Results: Acupuncture (traditional manual, electroacupuncture, and TEAS) and moxibustion (wheat, herbal cake, and warm uterus moxibustion) improve ER by regulating endometrial thickness, blood flow (e.g., reduced PI/RI), hormone levels (E2 and P), and type A endometrium ratio. Combined therapies (e.g., warm needling + acupuncture) further enhance efficacy. Mechanisms involve modulating autophagy (AMPK/mTOR pathway), pinopode-related molecules (LIF, integrin αvβ3), non-coding RNAs (miR-449a, circRNAs), and VEGF-mediated angiogenesis. Conclusion: Acupuncture and moxibustion are promising adjunctive therapies for ER enhancement in IVF-ET, but high-quality, standardized RCTs are needed to confirm efficacy, standardize protocols, and reduce bias.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.