Evidence map›Paper›PMID 41743628›Full record

ArticleCase reports in infectious diseases2026

A Case of Jarisch-Herxheimer Reaction After Ceftriaxone Initiation for Lyme Carditis in Postpartum Female.

Emily Taylor, Sunam Sujanani, Ammara Khan

Abstract read
In one paragraph

Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily TaylorUniversity of New England College of Osteopathic Medicine, Biddeford, Maine, USA.ORCID https://orcid.org/0009-0009-9217-6137
Sunam SujananiDepartment of Hospital Medicine, Northern Light Eastern Maine Medical, Bangor, Maine, USA.ORCID https://orcid.org/0000-0002-7664-6719
Ammara KhanDepartment of Hospital Medicine, Northern Light Eastern Maine Medical, Bangor, Maine, USA.ORCID https://orcid.org/0000-0002-1248-5434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lyme carditis is a complication occurring in 1%-5% of Lyme disease infections. It can lead to life-threatening cardiac conduction abnormalities. Treatment with antibiotics may trigger the Jarisch-Herxheimer reaction (JHR), an acute inflammatory response to spirochetal lysis. Here, we present a 32-year-old postpartum female with complete heart block and disseminated erythema migrans who developed JHR within hours of ceftriaxone initiation, requiring vasopressor support. Hemodynamic instability resolved within 24 h, with subsequent normalization of cardiac conduction within 72 h. This case highlights the importance of recognizing JHR, distinguishing it from allergic reactions and septic shock, and avoiding unnecessary antibiotic discontinuation.

Identifiers

PMID41743628
PMCPMC12930479

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.