ReviewFrontiers in cardiovascular medicine2026
Relationship between periodontitis and atrial fibrillation recurrence after ablation: a systematic review.
Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
Background: Atrial fibrillation (AF) recurrence after catheter ablation remains a significant clinical challenge, with chronic inflammation implicated in its pathogenesis. Periodontitis, a prevalent chronic inflammatory disease, may contribute to AF recurrence through systemic inflammation and microbial translocation. This systematic review synthesizes evidence on the association between periodontitis and AF recurrence post-ablation. Methods: MEDLINE, EMBASE, and Cochrane Library were searched from inception to January 2026. Observational studies evaluating periodontitis (diagnosed clinically, serologically, or via periodontal indices) and post-ablation AF recurrence in adults were included. Study quality was assessed using the Newcastle-Ottawa Scale. Narrative synthesis was performed due to methodological heterogeneity. Results: Three observational studies ( Conclusion: Periodontitis is consistently associated with higher AF recurrence after ablation, likely mediated by systemic inflammation and oral pathogen activity, highlighting periodontitis as a modifiable risk factor for AF recurrence.
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