ArticleBiomimetics (Basel, Switzerland)2026
Design Features of a Titanium Mesh for Guided Bone Regeneration and In Vivo Testing in Vitamin D3 Deficiency Condition.
Ekaterina Diachkova, Aglaya Kazumova, Andrei Shamanaev, Liubov Shcherbinina, Alexandr Gulyaev, Yuriy Vasil'ev, Pavel Petruk, Anzhela Brago, Yulianna Enina, Valerii Chilikov and 3 more
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In one paragraphArticle in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
13 authors.
Ekaterina DiachkovaDepartment of Oral Surgery, Borovskiy Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0003-4388-8911 Aglaya KazumovaDepartment of Oral Surgery, Borovskiy Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0009-0003-6481-6017 Andrei ShamanaevMedical Faculty, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya St., 8, Building 2, Moscow 119991, Russia.ORCID 0009-0009-8247-6419 Liubov ShcherbininaMedical Faculty, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya St., 8, Building 2, Moscow 119991, Russia.ORCID 0009-0007-0114-3619 Alexandr GulyaevMedical Faculty, Russian University of Medicine, Dolgorukovskaya Street 4, Moscow 127006, Russia.ORCID 0009-0003-7529-7216 Yuriy Vasil'evDepartment of Operative Surgery and Topographic Anatomy, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0003-3541-6068 Pavel PetrukMaxillofacial Surgery Department, Borovskiy Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0003-3686-2385 Anzhela BragoDepartment of Propedeutics of Dental Diseases, Medical Institute, Peoples' Friendship University of Russia Named After Patrice Lumumba, Moscow 117198, Russia.ORCID 0000-0001-8947-4357 Yulianna EninaDepartment of Operative Surgery and Topographic Anatomy, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0003-2511-9027 Valerii ChilikovDepartment of Operative Surgery and Topographic Anatomy, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0003-2819-0718 Hadi DarawshehDepartment of Operative Surgery and Topographic Anatomy, Sklifosovskiy Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0002-1899-1282 Ekaterina MakeevaAnatomy Department, Russian University of Medicine, Dolgorukovskaya Street 4, Moscow 127006, Russia.ORCID 0000-0003-4177-374X Svetlana TarasenkoDepartment of Oral Surgery, Borovskiy Institute of Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 8/2 Trubetskaya St., Moscow 119991, Russia.ORCID 0000-0001-8595-8864 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Prolonged tooth loss causes alveolar ridge atrophy, complicating implantation, especially in patients with impaired mineral metabolism. This study aimed to develop a personalized titanium mesh for guided bone regeneration and qualitatively evaluate its local tissue response in a vitamin D3-deficient rabbit model. A titanium mesh design has been developed in the form of a plate-shaped profile frame of a truncated pyramid with a solid upper base and perforated side faces. For testing in a rabbit model with vitamin D3 deficiency, a bone defect was created and repaired in the mandible using hydroxyapatite, an individual titanium mesh and a collagen membrane. Histological analysis was performed in the Laboratory of Digital Microscopic Analysis. The optimized geometry and parameters of the mesh openings contributed to effective vascularization and osteogenesis. In the postoperative period (3, 5 and 7 days), moderate edema and hyperemia were noted with their complete leveling by the 7th day (
Indexed as
3D printingalveolar process atrophybone graftingdental implantationguided bone regenerationindividualized titanium meshselective laser sintering
Identifiers
PMID41744537
PMCPMC12938668
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