Evidence map›Paper›PMID 41744541›Full record

ArticleBiomimetics (Basel, Switzerland)2026

Development of Three Alternative Strategies for the Binding of Cells to Functionalized DeepTip

Raquel Tabraue-Rubio, Laura Yuste Muñoz, Marcos Vázquez, Rafael Daza, Luis Colchero, María Eugenia Fernández-Santos, Manuel Elices, Fivos Panetsos, Gustavo V Guinea, José Pérez-Rigueiro

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adhesion and Friction in Biological and Bioinspired Systems.Biomimetics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Raquel Tabraue-RubioCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.ORCID 0000-0001-7974-689X
Laura Yuste MuñozCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.
Marcos VázquezDepartment of Cardiology, Gregorio Marañón General University Hospital and Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), 28007 Madrid, Spain.
Rafael DazaCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.ORCID 0000-0001-7883-648X
Luis ColcheroCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.ORCID 0000-0002-9673-0061
María Eugenia Fernández-SantosDepartment of Cardiology, Gregorio Marañón General University Hospital and Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), 28007 Madrid, Spain.ORCID 0000-0001-9229-0022
Manuel ElicesDepartamento de Ciencia de Materiales, ETSI Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
Fivos PanetsosBioactive Surfaces S.L., C/Puerto de Navacerrada 18, 28260 Galapagar, Madrid, Spain.ORCID 0000-0003-0897-411X
Gustavo V GuineaCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.
José Pérez-RigueiroCenter for Biomedical Technology, Universidad Politécnica de Madrid, 28223 Pozuelo de Alarcón, Madrid, Spain.ORCID 0000-0001-8298-8398

Funding

Comunidad de Madrid TecNanoBio TEC-2024/TEC-158Comunidad de Madrid. Spain MINA-CM P2022-BMD-7236European Commission ISOS (Grant Agreement number 101130454)European Commission THOR (Grant Agreement number 101099719)Ministerio de Ciencia, Innovación y Universidades PID2023-152058OB-I00
6 · The paper itself

Abstract

The efficient design of biohybrid materials requires controlling the interaction between the cell and the material for a wide range of possible combinations. Single cell force spectroscopy (SCFS), an atomic force microscopy (AFM) experimental procedure based on the binding of an individual cell to an AFM cantilever and the assessment of the adhesion force between the cell and a target substrate, represents one of the most promising alternatives to characterize the interaction between cell and material. However, SCFS relies on the efficient binding of the cell to the AFM in order to avoid drawbacks, such as the detachment of the cell. In this work, three different versatile and robust procedures are presented that allow for the binding of either non-adherent (CD4

Indexed as

atomic force microscopybiohybrid materialcrosslinking chemistrysingle cell force spectroscopy

Identifiers

PMID41744541
PMCPMC12938487

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.