Evidence map›Paper›PMID 41744779›Full record

ArticleCells2026

Heat-Treated

Laura Rago, Guillermo García-Lainez, Miren Maicas, Ester Pardo, Veronica Navarro, Jennifer Redondo, Ferran Balaguer, Roberto Martinez, Silvia Llopis, Agata Rybicka and 3 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laura RagoArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0000-0003-0698-9289
Guillermo García-LainezArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0000-0003-1459-0702
Miren MaicasArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0000-0003-1404-5552
Ester PardoArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.
Veronica NavarroArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.
Jennifer RedondoArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0009-0006-2241-840X
Ferran BalaguerArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.
Roberto MartinezArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.
Silvia LlopisArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0009-0003-3263-8113
Agata RybickaArcher Daniels Midland International Sarl, 1066 Epalinges, Switzerland.
Adrián Florit-RuizArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.
Empar ChenollArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0000-0002-6891-3573
Patricia MartorellArcher Daniels Midland, Nutrition, R&D Health & Wellness, Biopolis S.L. Parc Cientific Universitat de València, C/Catedrático Agustín Escardino Benlloch, 9, 46980 Paterna, Spain.ORCID 0000-0001-5689-8399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine osteoarthritis is a progressive degenerative joint condition characterized by inflammation, structural damage, pain, and impaired joint function. Osteoarthritis risk is influenced not only by well-established factors such as age, genetics, obesity and underlying arthropathies, but also by systemic conditions such as low-grade inflammation and sarcopenia. Current interventions are primarily focused on pain relief rather than mitigating physiological impairment, despite recent veterinary guidelines. In this study, several preclinical models were employed to identify postbiotic candidates with potential to promote canine joint health. An initial screening of nine heat-treated bacterial strains identified two

Indexed as

anti-inflammatory activityCaenorhabditis eleganscanine osteoarthritischondrocytespostbiotics

Identifiers

PMID41744779
PMCPMC12939062

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.