Evidence map›Paper›PMID 41745004›Full record

ArticleGels (Basel, Switzerland)2026

Response Surface Optimization of Curcumin Oil-Loaded Dual-Crosslinked PVOH/CMC/Gellan Gum Hydrogels with Controlled Release and Anti-Inflammatory Activity.

Suthaphat Kamthai, Ratana Banjerdpongchai, Aree Deenu, Kamonwan Tachai, Patompong Khaw-On

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suthaphat KamthaiLanna Rice Research Center, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0003-3710-8464
Ratana BanjerdpongchaiDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-0555-0821
Aree DeenuDivision of Food Science and Technology, School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
Kamonwan TachaiDivision of Packaging Technology, School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
Patompong Khaw-OnLanna Rice Research Center, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0002-9965-5319

Funding

Fundamental Fund 2024, Chiang Mai University FF009/67
6 · The paper itself

Abstract

Wound-related inflammatory pain is a major contributor to wound healing success and requires wound-specific therapeutic platforms with minimal systemic adverse effects. This study builds a dual-crosslinked polyvinyl alcohol (PVOH)/carboxymethyl cellulose (CMC)/gellan gum hydrogel system with optimized mechanical strength and sustained anti-inflammatory drug delivery by developing predictive mathematical models using response surface methodology with central composite design. The effects of citric acid (5-15%

Indexed as

anti-inflammatorycontrolled releasecurcumindual-crosslinked hydrogelgellan gummacrophage modulationpain reliefresponse surface methodologyROS inhibition

Identifiers

PMID41745004
PMCPMC12940083

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.