Evidence map›Paper›PMID 41745053›Full record

ArticleGels (Basel, Switzerland)2026

Design and Optimization of Thermosensitive Hydrogels Combined with Lipid Nanotechnology for Topical Curcumin Application.

Daniela Vergara, Benjamín Vega, Claudia Sanhueza, Mariela Bustamante, Francisca Acevedo, Olga López

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniela VergaraCenter of Excellence in Translational Medicine-Scientific Technological Bioresource Nucleus (CEMT-BIOREN), Laboratory of Pharmaceutical and Cosmetic Bioproducts, Faculty of Medicine, Universidad de La Frontera, Temuco 4811230, Chile.ORCID 0009-0009-0654-2322
Benjamín VegaMillennium Nucleus Bioproducts, Genomics and Environmental Microbiology (BioGEM), Avenida España 1680, Valparaíso 2390123, Chile.
Claudia SanhuezaCenter for Resilience, Adaptation and Mitigation (CReAM), Universidad Mayor, Temuco 4780000, Chile.ORCID 0000-0001-5558-5032
Mariela BustamanteCenter of Food Biotechnology and Bioseparations-BIOREN, Universidad de La Frontera, Temuco 4811230, Chile.
Francisca AcevedoCenter of Excellence in Translational Medicine-Scientific Technological Bioresource Nucleus (CEMT-BIOREN), Laboratory of Pharmaceutical and Cosmetic Bioproducts, Faculty of Medicine, Universidad de La Frontera, Temuco 4811230, Chile.ORCID 0000-0002-7060-0656
Olga LópezDepartment of Chemical and Surfactant Technology, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), C/Jordi Girona 18-26, 08034 Barcelona, Spain.

Funding

Agencia Nacional de Investigación y Desarrollo (ANID) from the Chilean Government through FONDECYT Iniciación Project 11240998
6 · The paper itself

Abstract

A novel co-encapsulation platform based on curcumin-loaded liposomes (Cur-Lip) incorporated into thermosensitive hydrogels (TSH) was developed to address the physicochemical and biological limitations of topical curcumin (Cur) delivery. Response Surface Methodology (RSM) was used to optimize Pluronic

Indexed as

curcumindelivery systemliposomethermosensitive hydrogeltopical administration

Identifiers

PMID41745053
PMCPMC12940228

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.