Evidence map›Paper›PMID 41745324›Full record

ReviewJournal of cardiovascular development and disease2026

Cor Triatriatum Dexter: The Largest Comprehensive Review in the Field on 124 Worldwide Cases (1968-Now).

Pier Paolo Bassareo, Erica Franco, Sophie Duignan, Massimo Chessa, Mariateresa Cascio, Colin Joseph McMahon, Kevin Patrick Walsh, Marco Alfonso Perrone

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pier Paolo BassareoSchool of Medicine, University College of Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-8374-0260
Erica FrancoDivision of Cardiology, Ospedale Civico di Chivasso, 10034 Chivasso, Italy.
Sophie DuignanChildren's Health Ireland at Crumlin, D12 N512 Dublin, Ireland.ORCID 0000-0002-0384-1193
Massimo ChessaAdult Congenital Heart Disease UNIT, Paediatric and Adult Congenital Heart Centre, IRCCS-Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy.
Mariateresa CascioSurrey and Sussex Healthcare NHS Trust, Redhill RH1 5RH, UK.
Colin Joseph McMahonSchool of Medicine, University College of Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0003-0337-9338
Kevin Patrick WalshSchool of Medicine, University College of Dublin, D04 V1W8 Dublin, Ireland.
Marco Alfonso PerroneDivision of Cardiology and CardioLab, Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-0511-2621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCor triatriatum dexter (CTD) is a rare congenital heart defect where a membrane divides the right atrium into two chambers, resulting from the incomplete regression of the right valve of the sinus venosus. Due to its rarity, only individual case reports and a limited number of case series have been published to date. This study constitutes the most extensive comprehensive review conducted in this area. Eight factors were evaluated: age at diagnosis, sex, clinical presentation, electrocardiographic findings, imaging (ultrasound, CT, or MRI), associated cardiac anomalies, and patient outcomes.

methodsThe electronic databases PubMed and Scopus were searched from their inception until 30 October 2025. Only case reports and case series were considered for inclusion. Studies involving foetuses, autopsies, and animals were excluded. The collected data were primarily presented as percentages.

resultsOne hundred fourteen studies were found encompassing 124 patients. The mean age at diagnosis was 33.3 ± 9.4 years The most common clinical presentations were dyspnoea (44.3%) and cyanosis (29.5%). The most commonly encountered ECG changes were supraventricular tachycardia/atrial flutter/atrial fibrillation (33.3%) and right bundle branch block (22.6%). On chest X-ray, cardiomegaly was noted in 46.5%. CTD was suspected or diagnosed by echocardiography in 95.2% of cases. The diagnosis was confirmed by CT and/or MRI in 34.1% of cases. A concomitant congenital heart defect was found in 67.7%, especially in the form of all kinds of atrial septal defect (38.1%) and of right valvular and right ventricular involvement (20.1%). An outcome was reported in 97/124. Surgical correction was the treatment of choice in 51.6%. Since 1991, a percutaneous approach has been employed in selected cases (5.1%). Conservative management was the treatment of choice in 43.3%. The mortality rate was 8.2%. DISCUSSION: The principal limitation of this systematic review lies in its reliance solely on case reports and small case series, reflecting the absence of large-scale studies on CTD. Nonetheless, it constitutes the most comprehensive analysis available to date.

Indexed as

cardiac magnetic resonance imagingcomputed tomographycongenital heart diseasecor triatriatum dextercor triatriatum dextrumechocardiography

Identifiers

PMID41745324
PMCPMC12941072

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.