Evidence map›Paper›PMID 41745595›Full record

ArticleMetabolites2026

Evidence for a Cytokine-Sensitive Network of Iron-Associated Genes That Protects Pancreatic Islets Against Ferroptosis.

Kira G Slepchenko, Grace P Counts, Poonam R Sharma, Si Chen, Kathryn L Corbin, Farhan M Qureshi, Robert A Colvin, C Martin Lawrence, Craig S Nunemaker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kira G SlepchenkoDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine (HCOM), Ohio University, Athens, OH 45701, USA.ORCID 0000-0001-7805-9262
Grace P CountsDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine (HCOM), Ohio University, Athens, OH 45701, USA.ORCID 0000-0002-1275-3945
Poonam R SharmaDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA 22903, USA.
Si ChenAdvanced Photon Source, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0001-6619-2699
Kathryn L CorbinDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine (HCOM), Ohio University, Athens, OH 45701, USA.
Farhan M QureshiMedical Scientist Training Program, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, School of Medicine, University of Miami Miller, Miami, FL 33136, USA.
Robert A ColvinMolecular and Cellular Biology Program, Ohio University, Athens, OH 45701, USA.ORCID 0000-0003-1376-4563
C Martin LawrenceDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA.ORCID 0000-0002-5398-466X
Craig S NunemakerDepartment of Biomedical Sciences, Heritage College of Osteopathic Medicine (HCOM), Ohio University, Athens, OH 45701, USA.ORCID 0000-0003-2894-3388

Funding

NIDDK NIH HHS R01DK089182NIDDK NIH HHS R15DK121247Ohio University Donald Clippinger Fellowship none
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-cellferroptosishepcidinIL-1βIL-6ironisletslipocalin2oxidative stressreactive oxygen speciesSteap4

Identifiers

PMID41745595
PMCPMC12943054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.