Toxicometabolomics Characterization of Two N1-Sulfonated Dimethyltryptamine Derivatives in Zebrafish Larvae and Human Liver S9 Fractions Using Liquid Chromatography-High-Resolution Mass Spectrometry.

Prajwal Punnamraju, Sascha K Manier, Selina Hemmer, Matthias Grill, Philip Schippers, Jennifer Herrmann, Markus R Meyer

Abstract read

In one paragraph

Article in Metabolites, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Prajwal PunnamrajuExperimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), PharmaScienceHub (PSH), Saarland University, 66424 Homburg, Germany.

Sascha K ManierExperimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), PharmaScienceHub (PSH), Saarland University, 66424 Homburg, Germany.

Selina HemmerExperimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), PharmaScienceHub (PSH), Saarland University, 66424 Homburg, Germany.

Matthias GrillMiHKAL GmbH, Allschwil, CH-4123 Basel, Switzerland.

Philip SchippersExperimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), PharmaScienceHub (PSH), Saarland University, 66424 Homburg, Germany.ORCID 0000-0003-3036-326X

Jennifer HerrmannHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), PharmaScienceHub (PSH), Saarland University, Campus E 8.1, 66123 Saarbrücken, Germany.ORCID 0000-0003-3398-9938

Markus R MeyerExperimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), PharmaScienceHub (PSH), Saarland University, 66424 Homburg, Germany.ORCID 0000-0003-4377-6784

Funding

European Union and Saarland University Marie Skłodowska-Curie CO-FUND-Action of the European Union [101081463]

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

human liver S9 fractionsliquid chromatography–high-resolution mass spectrometrynovel psychoactive substancestoxicometabolomicszebrafish larvae

Identifiers

PMID41745615

DOI10.3390/metabo16020134

PMCPMC12943172

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.