Evidence map›Paper›PMID 41745934›Full record

ArticleVeterinary sciences2026

Ultrasonographic Evidence of Synovitis Correlates with Synovial Citrate and TBARS in Equine Osteoarthritis.

Anna Paula Barreira, Thaís Moreira, Rafaela Silva, Letícia Nunes, Adriana Lioi, Elizabeth Kraus, Vittoria Altheman, Marcela Ribeiro, Carla Leite, Andreza Silva and 4 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anna Paula BarreiraDepartment of Veterinary Medicine and Surgery, Veterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.ORCID 0000-0002-1243-5939
Thaís MoreiraVeterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.ORCID 0009-0009-4328-6049
Rafaela SilvaVeterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.
Letícia NunesVeterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.
Adriana LioiBrazilian Jockey Club (JCB), Rio de Janeiro 22470-060, Brazil.
Elizabeth KrausBrazilian Jockey Club (JCB), Rio de Janeiro 22470-060, Brazil.
Vittoria AlthemanPostgraduate Program in Animal Biotechnology, Regenerative Medicine Lab, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-970, Brazil.ORCID 0000-0003-0540-9932
Marcela RibeiroPostgraduate Program in Animal Biotechnology, Regenerative Medicine Lab, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-970, Brazil.ORCID 0009-0008-8102-1941
Carla LeitePostgraduate Program in Veterinary Medicine, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.
Andreza SilvaDepartment of Veterinary Medicine and Surgery, Veterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.ORCID 0000-0002-4254-5856
Fernando AlmeidaDepartment of Veterinary Medicine and Surgery, Veterinary Institute, Rural Federal University of Rio de Janeiro (UFRRJ), Seropedica 23890-000, Brazil.ORCID 0000-0002-0418-2775
Gilson Santos JuniorLaboratory of Metabolomics (LabMet), Department of Genetics, State University of Rio de Janeiro (UERJ), Rio de Janeiro 20550-013, Brazil.
Daniel LessaDepartment of Pathology and Veterinary Clinic, Federal Fluminense University, Niteroi 24230-340, Brazil.ORCID 0000-0002-7123-8265
Ana Liz AlvesPostgraduate Program in Animal Biotechnology, Regenerative Medicine Lab, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-970, Brazil.

Funding

Rio de Janeiro Research Foundation (FAPERJ) 2017/12815-0Rio de Janeiro Research Foundation (FAPERJ) E-26/201.259/2021São Paulo Research Foundation (FAPESP) 2017/12815-0São Paulo Research Foundation (FAPESP) 2017/14460- 4
6 · The paper itself

Abstract

Osteoarthritis (OA) is a degenerative joint disease that affects humans and animals worldwide. Its early diagnosis remains challenging due to subtle clinical signs and late radiographic changes. This study aimed to explore candidate biomarkers associated with spontaneous OA and to investigate their correlation with ultrasonographic scores to support early diagnosis. Clinical, radiographic, and ultrasonographic evaluations were performed on 52 equine metacarpophalangeal joints, with and without OA, allowing joint scoring and classification into osteoarthritis (OAG) and control groups. Synovial fluid samples were analyzed for cartilage degradation (C2C), untargeted

Indexed as

horsesjoint diseasemetabolomicsoxidative stress

Identifiers

PMID41745934
PMCPMC12945042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.